The Evolution of the Treatment of Non-Small Cell Lung Cancer: A Shift in Surgical Paradigm to a More Individualized Approach

As the understanding of the natural progression of smaller peripheral lung nodules grows, the treatment options and existing paradigms continue to change. One area that is under intense study involves ground glass nodules (GGOs), which are detected by high resolution CT scans. The authors summarize the recent efforts to classify the aggressiveness of GGOs on imaging with the resulting pathology noted after surgical resection and discuss how such lesions can be over and under treated based on existing classification systems. The authors also discuss algorithms to aid in individualized patient selection for sublobar resections with such lesions.