The outcome of perioperative prophylactic glucocorticoids for heart surgery in infants was unknown, and this study aimed to determine the effectiveness using a multicenter, randomized trial. Out of the infants who received either a dose of methylprednisolone or a placebo, the likelihood of a worse outcome did not significantly differ.
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Methylprednisolone for Heart Surgery in Infants—A Randomized, Controlled Trial
Submitted by: Cameron Lind
Source: The New England Journal of Medicine
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Author(s): Kevin D. Hill, M.D., M.S.C.I., Prince J. Kannankeril, M.D., M.S.C.I., Jeffrey P. Jacobs, M.D., H. Scott Baldwin, M.D., Marshall L. Jacobs, M.D., Sean M. O’Brien, Ph.D., David P. Bichel, M.D., Eric M. Graham, M.D., Brian Blasiole, M.D., Ph.D., Ashraf Resheidat, M.D., Adil S. Husain, M.D., S. Ram Kumar, M.D., Ph.D., et al., for the STRESS Network Investigators
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