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George Krasopoulos
George Krasopoulos, MD, PhD, MRCS,FRCS-CTh
Background
Consultant in General Adult Cardiac Surgery, Oxford, UK (2013 - today)
Hon. Professon in Cardiac Surgery, University of Cumbria, UK (2017-today)
Hon. Senior Clinical Lecturer in Cardiac Surgery, University of Oxford (2015 - today)
Specialist Lecturer in Cardiothoracic Surgery, University of Buckingham, UK (2015-today)
Specialist Lecturer in Cardiothoracic Surgery, Anglia Ruskin Univeristy, UK (2016-today)
Non-executive Director (Chair), Liga College, UK (2016-today)
Consultant Adult Cardiac, Adult Structural & Adult Congenital Heart Disease, Thessaloniki, Greece (2010-2013)
Consultant Adult Cardiac Surgeon, London, UK (2009-2010)
Consultant Adult Cardiac Surgeon, Liverpool, UK (2008-2009)
Senior Registrar in Cardiac Surgery, Royal Brompton & London Chest Hospitals, London, UK (2007-2008)
Fellowship in Cardiovascular & Aortic Surgery, Toronto General Hospital, Toronto, Canada (2006-2007)
Cardiothoracic Specialist Registrar (Adult & Paediatric), London, UK (2001 - 2006)
Cardiothoracic Junior Residency, London, UK (1999 - 2000)
Surgical Residence UK (1996 - 1999) & Greece (1994-1996)
Other Interests
Minimally invasive cardiac surgery
Aortic aneurysm surgery
Aortic valve repairs
Aortic root repairs
Mitral valve repairs
Tricuspid valve repairs
Heart valve replacements
Coronary artery by pass surgery (on pump & off pump)
Ischaemic heart disease - LV reconstruction
Surgery for atrial arrhythmias
TAVR
Surgery for pericardial disease
Coagulation & Platelet function
Pulmonary embolism
Adult congenital surgery
Research
Peer Review Journals
Influence of coronary territory on flow profiles of saphenous vein grafts
S Amin · RW Werner· PL Madsen · G Krasopoulos· DP Taggart
J. Cardiothoracic Surg. 2018 13:23 doi.org/10.1186/s13019-018-0709-6
· 1.413 Impact Factor
Effect of glycaemic control on complications following cardiac surgery: Literature review.
M. Navaratnarajah · R. Rea · R. Evans · F. Gibson · C. Antoniades · A. Keiralla · M. Demosthenous · G. Kassimis · G. Krasopoulos
J. Cardiothoracic Surg. 2018 13(1):10; doi 10.1186/s13019-018-0700-2
· 1.413 Impact Factor
Influence of external stenting on venous graft flow parameters in coronary artery bypass grafting: a randomized study
S Amin · RW Werner· PL Madsen · G Krasopoulos· DP Taggart
Intera. CardioVasc and Thor Surg 2018 1–6, doi:10.1093/icvts/ivy007
· 1.112 Impact Factor
Cardiac MRI T1-mapping Accurately Predicts Functional Recovery Post-Revascularization Without the Need for Gadolinium-based Contrast Agents
A Liu · RS Wijesurendra · J Liu · A Greiser · B Raman · M Petrou · G Krasopoulos· SK Piechnik· S Neubauer · VM Ferreira
Circulation 2018; (accepted for publication)
· 14.43 Impact Factor
Procedural and thirty-day outcomes following transferral implantation of the fully reposition able and retrievable Lotus valve without routine pre-dilatation in a consecutive patient chart: a single centre experience
N Ruparelia · K Thomas · JD Newton · K Grebenik · A Keiralla · G Krasopoulos· R Sayeed · AP Banning · RK Kharbanda.
Cardiovasc Revasc Med. 2017Nov; S1553-8389(17)30408-6. doi: 10.1016/j.carrev.2017.10.01
· 1.15 Impact Factor
Transfemoral Transcatheter Aortic Valve-in Valve Implantation for Aortic Valve Bioprosthesis Failure With the Fully Repositionableand Retrievable Lotus Valve: A Single-Center Experience.
N Ruparelia · K Thomas · JD Newton · K Grebenik · A Keiralla · G Krasopoulos· R Sayeed · AP Banning · RK Kharbanda.
J Invasive Cardiol. 2017 Sep;29(9):315-319. Epub 2017 Jul 15.
· 1.112 Impact Factor
Redox-sensitive regulation of cystine gamma-lyase (CSE) and the potential protective role of hydrogen sulfide (H2S) in the human heart.
A Tarum · C Psarros · F. Sanna · L. Herdman · I Akoumianakis · AS Antonopoulos · R Sayeed · G Krasopoulos· S Chuaiphichai · KM Channon · C Antoniades
European Heart Journal, 2017; 38, suppl_1, https://doi.org/10.1093/eurheartj/ehx493.P5388
· 15.203 Impact Factor
Echocardiographic pre-operative early mitral inflow velocity-toearly diastolic strain rate ratio predicts postoperative paroxysmal atrial fibrillation in patients undergoing CABG surgery.
G Sangha · EK Oikonomou · AS Antonopoulos · L. Herdman · R Sayeed · G Krasopoulos· M Petrou · KM Channon · C Antoniades
European Heart Journal, 2017; 38, suppl_1, https://doi.org/10.1093/eurheartj/ehx493.P5243
· 15.203 Impact Factor
False Positive Transit Time Flowmetry Graft Failure in Multivessel Coronary Spasm following Off-Pump Coronary Artery Bypass Grafting
G Kassimis · G Krasopoulos
Case Reports in Cardiology 2017; 3186047 DOI: 10.1155/2017/3186047
Detecting human coronary inflammation by imaging perivascular fat
S Antonopoulos · F Sanna · N Sabharwal · G Lazanos · EK Oikonomou · L Herdman · M Margaritis · C Shirodaria · AM Kampoli · I Akoumianakis · M Petrou · R Sayeed · G Krasopoulos· C Psarros · P Ciccone · CM Brophy · J Digby · A Kelion · R Uberoi · S Anthony · N Alexopoulos · D Tousoulis · S Achenbach · S Neubauer · KM Channon · C Antoniades
Science Translational Medicine Journal 2017; 9 (398) DOI: 10.1186/s12968-016-0318-
· 15.843 Impact Factor Media: The Guardian, NBC, FT, BBC News, US newspapers, French media
Predictive value of telomere length on outcome following acute myocardial infarction: Evidence for contrasting effects of vascular vs. blood oxidative stress
M Margaritis · F Sanna · G Lazanos · I Akoumianakis · S Patel · AS Antonopoulos · C Duke · L Herdman · C Psarros · EK Oikonomou · C Shinodata · M Petrou · R Sayeed · G Krasopoulos · R Lee · D Tousoulis · KM Channon · C Antoniades
European Heart Journal 2017 Apr 24. doi: 10.1093/eurheartj/ehx177
· 15.203 Impact Factor
A Prospective Study of External Stenting of Saphenous Vein Grafts to the Right Coronary Artery: The VEST II Study
DP Taggart · S Amin · J Djordjevic · EK Oikonomou · S Thomas · A-M Kampoli · N Sabharwal · C Antoniades · G Krasopoulos
Eur. J. Cardio-Thoracic Surg. 2017;51(5):952-958. doi: 10.1093/ejcts/ezw438.
· 2.81 Impact Factor
Splenic T1-mapping: a novel quantitative method for assessing adenosine stress adequacy on cardiovascular magnetic resonance imaging
A Liu · RS Wijesurendra · R Ariga· M Mahmod · E Levelt · A Greiser · M Petrou · G Krasopoulos· JC Forfar · RK Kharbanda· C Channon · S Neubauer· SK Piechnik · VM Ferreira
J. Cardiovasc. Mag. Reson. 2017 Jan 13;19(1):1. doi: 10.1186/s12968-016-0318-2.
· 5.75 Impact Factor
European real world trans-catheter aortic valve implantation: Systematic review and meta-analysis of European national registries
G Krasopoulos· F Falconieri· U Benedetto · J Newton · R Sayeed· RK Kharbanda · A Banning
J. Cardiothoracic Surg. (2016) 11:159. doi 10.1186/s13019-016-0
· 1.413 Impact Factor
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.
Reilly S · Liu X · Carnicer R · Recalde A · Muszkiewicz A · Jayaram R · Carena M · Wijesurendra R · Stefanini M · Surdo NC · Lomas O · Ratnatunga C · Sayeed R · Krasopoulos G · Rajakumar T · Bueno- Orovio A · Verheule S · Fulga T · Rodriguez B · Schotten U · Casadei B.
Science Translational Medicine May 2016; 8(340):340ra74-340ra74
• 15.84 Impact Factor
Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR- γ/Adiponectin Signaling
Antonopoulos AS · Margaritis M · Verheule S · Recalde A · Sanna F · Herdman L · Psarros C · Nasrallah H · Coutinho P · Akoumianakis I · Brewer AC · Sayeed R · Krasopoulos G · Petrou M · Tarun A · Tousoulis D · Shah AM · Casadei B · Channon KM · Antoniades C.
Circulation Research · 2016 Mar 4;118(5):842-55. doi: 10.1161
11.04 Impact Factor
Loss of Myocardial nNOS Mediated by Upregulation of miR-31 in Human Atria Contributes to Begetting of Atrial Fibrillation
X Liu · S Reilly · R Carnicer · A Recalde · A Muszkiewicz · R Jayaram · M C Carena · M Stefanini · R Wijesurendra · O Lomas · R Sayeed · G Krasopoulos · A Bueno-Orovio · B Rodriguez · B Casadei.
Biophysical Journal, February 2016; vol. 110, issue 3, p. 451a
• 3.972 Impact Factor
New Roles of the Interplay Between Endothelin and Insulin-like Growth Factor 1 in the Regulation of Vascular Redox State In Patients With Type 2 Diabetes and Coronary Atherosclerosis
I. Akoumianakis · M. Margaritis · F. Sanna · L. Herdman · C. Psarros · R. Sayeed · G. Krasopoulos · P. Wohlfart · K. Channon · C. Antoniades
Circulation 2015; 132, A18289
· 14.43 Impact Factor
Adiponectin as a Link Between Type 2 Diabetes and Vascular NADPH Oxidase Activity in the Human Arterial Wall: The Regulatory Role of Perivascular Adipose Tissue
A S Antonopoulos · M Margaritis · P Coutinho · C Shirodaria · C Psarros · L Herdman · F Sanna · R De Silva · M Petrou · R Sayeed · G Krasopoulos · R Lee · J Digby · S Reilly · C Bakogiannis · D Tousoulis · B Kessler · B Casadei · K M Channon · C Antoniades
Diabetes 12/2015; 64(6),2207-2219. DOI:10.2337/db14-1011
· 8.47 Impact Factor
Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial- fibrillation-induced electrical remodelling in man.
S Reilly · X Liu · R Carnicer · T Rajakumar · R Sayeed · G Krasopoulos · S Verheule · T Fulga · U Schotten · B Casadei
The Lancet 02/2015; 385:S82. DOI:10.1016/S0140-6736(15)60397-X
· 45.22 Impact Factor
Increased Nadph-Oxidase Activity Is Associated With Reduced Telomere Length in the Human Vascular Wall: The Influence of Oxidative Stress on Biological Aging.
M Margaritis · S Patel · AS Antonopoulos · L Herdman · F Sanna · K Ananthan · M Petrou · G Krasopoulos · K M Channon · C Antoniades
Arteriosclerosis, Thrombosis, and Vascular Biology 2015; 35 (Suppl 1), A655-A655
· 6.0 Impact Factor
P106 * Loss of myocardial nNOS in human atrial fibrillation (AF) shortens action potential duration (APD) by increasing Ito: Implications for AF-induced electrical remodelling.
X Liu · S Reilly · R Carnicer · A Recalde · G Krasopoulos · R Sayeed · R Desilva · B Casadei
Cardiovascular Research 07/2014; 103(suppl 1):S18. DOI:10.1093/cvr/cvu082.47
· 5.81 Impact Factor
A MiR-31-dependent Loss of Dystrophin & Nnos in the Human Atria Plays a Key Role in Atrial Fibrillation-induced Electrical Remodelling.
S Reilly · X Liu · R Carnicer · T Rajakumar · R Sayeed · G Krasopoulos · S Verheule · T Fulga · U Schotten · B Casadei
Circulation 2014; 130 (Suppl 2), A17767-A17767
· 14.43 Impact Factor
Perivascular adipose tissue around the left internal mammary artery regulates oxidative stress in this graft through PI3k/Akt-mediated down-regulation of p22phox subunit of NADPH-oxidase.
M Margaritis · A Antonopoulos · P Coutinho · R Sayeed · R De Silva · M Petrou · G Krasopoulos · R Lee · K M Channon · C Antoniades.
European Heart Journal 2014 vol. 35, pp. 1200-1201.
· 15.203 Impact Factor
Myocardial redox state as a regulator of PPAR-gamma signalling in epicardial adipose tissue of patients with ischemic heart disease: insights from the Oxford CABG Bioresource.
A Antonopoulos · M Margaritis · P Coutinho · C Psarros · D Tousoulis · G Krasopoulos · M Petrou · B Casadei · K M Channon · C Antoniades.
European Heart Journal 2014 vol. 35, pp. 446-446.
· 15.203 Impact Factor
Reply to actis dato et Al. (I). G Krasopoulos · P Goldstraw
European journal of cardio-thoracic surgery 03/2012; 41(3):725. DOI:10.1093/ejcts/ezr088
· 2.81 Impact Factor
The effect of prehospital time related variables on mortality following severe thoracic trauma. E Kidher · G Krasopoulos · T Coats · A Charitou · P Magee · R Uppal · T Athanasiou
Injury 05/2011; 43(9):1386-92. DOI:10.1016/j.injury.2011.04.014
· 2.46 Impact Factor
Minimally invasive repair of pectus excavatum deformity G Krasopoulos · P Goldstraw
European journal of cardio-thoracic surgery 02/2011; 39(2):149-58. DOI:10.1016/j.ejcts.2010.07.019
· 2.81 Impact Factor
Editorial: Eur. J. Cardiothorac. Surg. 2011; 39(2): 159 – 159 by F. Robicsek
Economic analysis of esophageal stenting for management of malignant dysphagia C Rao · A Haycock · E Zacharakis · G Krasopoulos · D Yakoub · A Protopapas · A Darzi · G B Hanna · T Athanasiou
Diseases of the Esophagus 02/2009; 22(4):337-47. DOI:10.1111/j.1442-2050.2008.00916.x
· 2.06 Impact Factor
Aspirin "resistance" and risk of cardiovascular morbidity: Systematic review and meta-analysis
G Krasopoulos · S J Brister · W S Beattie · M R Buchanan.
BMJ 02/2008; 336(7637):195-8. DOI:10.1136/bmj.39430.529549.BE
· 16.38 Impact Factor
Editorial: BMJ, 2008 336: 166-167 by G. Biondi-Zoccai & M. Lotrionte
Media: - TV News & Newspapers: CNN, CTV, Ch-4, Daily Telegraph, Washington Post
Web Pages: National Institute of Health Research – DARE (NHS), The Heart, British Heart Foundation, British Carciovascular Society, MedPage Today, Irish Med. News, Englemed News
Custom-tailored valved conduit for complex aortic root disease
G Krasopoulos · T E David · S Armstrong
The Journal of thoracic and cardiovascular surgery 02/2008; 135(1):3-7 / DOI:10.1016/j.jtcvs.2007.06.016
· 3.99 Impact Factor
Selected article by CTSNet - Jan 2014
Invited commentary – Self and parental assessment after minimally invasive repair of pectus excavatum: Lasting satisfaction after bar removal
P Goldstraw · G Krasopoulos
The Annals of thoracic surgery 06/2007; 83(5):1849. DOI:10.1016/j.athoracsur.2007.02.038
· 3.65 Impact Factor
Nuss procedure improves the quality of life in young mate adults with pectus excavatum deformity
G Krasopoulos · M Dusmet · G Ladas · P Goldstraw
European Journal of Cardio-Thoracic Surgery 02/2006; 29(1):1-5 / DOI:10.1016/j.ejcts.2005.09.018
· 2.81 Impact Factor
Clampless Arterial Coronary Artery Bypass Grafting with the Use of Magnetic Coupling Devices.
T Athanasiou · H Ashrafian · H Asrafian · G Krasopoulos · S Purkayastha · V Malinowski · S Al-Ruzzeh · B Glenville · R De La Stanbridge · R Casula
Journal of Cardiac Surgery 01/2006; 21(1):69-74; discussion 75-6. DOI:10.1111/j.1540-8191.2006.00172.x
· 0.89 Impact Factor
Emergency thoracotomy in the pre-hospital setting: a procedure requiring clarification.
T Athanasiou · G Krasopoulos · P Nambiar · T Coats · M Petrou · P Magee · R Uppal
European Journal of DOI:10.1016/j.ejcts.2004.03.016
· 2.81 Impact Factor
Sclerosing mediastinitis with aortic valve regurgitation and aortic root dilatation.
G St Krasopoulos · M Ibrahim · G Venn
Journal of the Royal Society of Medicine 03/2000; 93(2):83.
· 2.02 Impact Factor
Left Atrial Appendage Occlusion with the Amplatzer AmuletTM for Stroke Prevention in Atrial Fibrillation: The First Case in Greece.
A Tzikas · L Karagounis · M Bouktsi · A Drevelegas · D Parcharidou · S Ioannidis · G Krasopoulos · G Giannakoulas
Hell J Cardiol 2013 Sep-Oct;54(5):408-412.
· 1.227 Impact Factor
Greek guidelines for the use of antiplatelet agents on primary and secondary prevention of cardiovascular diseases.
I Goudevenos, G Krasopoulos, A Tselepis et al
Hell J Cardiol 2013 Feb. 2013.
· 1.227 Impact Factor
Oesophageal leiomyoma, a rare tumour. Presentation of two cases.
M Douzinas, G Krasopoulos, G Lazopoulos, N Haroulis.
Hell J CardiolActa Chirur. Hell. 1996, Vol. 6 (Suppl.): 16
Book Chapters
Cases in Adult Congenital Heart Disease - Surgical repair of Ebstein’s anomaly.
G. Krasopoulos, P. Catarino, H. Uemura
Publisher: Elsevier, Prof. M. Gatzoulis
Hospital Surgery - Thoracic Trauma.
G. Krasopoulos, S. S. Panesar, T. Athanasiou
Publisher: Cambridge University Press, Prof. A. Darzi
Additional Educational Information
FRCS-CTh - Intercollegiate Cardiothoracic Specialty Examination (Royal College of Surgeons of England, 2005)
MRCS - Surgical Board Examination (Royal College of Surgeons of England, 1998)
PhD (University of Athens, 1999)
MD (Athems Medical School, 1993)
Printer-friendlyPractice Areas
- Cardiac
- Aorta
- Electrophysiology/arrhythmia
- Congenital
- Adult congenital procedures
- Coronary disease
- Minimally Invasive
- Endocarditis
- Extracorporeal circulation
- Great vessels
- Heart failure
- Aortic valve disease
- Transcatheter
- Mitral valve disease
- Pericardium
- Tricuspid valve disease
- Valve disease
- Vascular