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Journal and News Scan
While seasonal patterns suggest cold weather influences the incidence of acute type A aortic dissection, the impact of subjective thermal stress on dissection risk remains poorly characterized. This retrospective multicenter study examined environmental triggers of acute type A aortic dissection in 548 German patients between 1996 and 2016. Subjective cold exposure, perceived as wind chill, significantly increased dissection odds by up to 50 percent, peaking 3-4 days before events. Elevated atmospheric pressure and low dew point also increased risk, while lower humidity showed modest protection. The acute temporal pattern suggests that cold-induced sympathetic activation, vasoconstriction, and blood pressure surges precipitate dissection in vulnerable individuals. These interesting findings emphasize that perceived environmental stress outweighs ambient temperature in triggering acute aortic events, highlighting opportunities for targeted prevention during adverse weather.
The PROCTOR trial randomized 220 post-coronary artery bypass grafting patients with saphenous vein graft (SVG) failure to native vessel percutaneous coronary intervention (PCI) (n=108) or SVG PCI (n=112). At one-year, major adverse cardiac events occurred in 34 percent with native PCI vs 19 percent with SVG PCI (HR 2.14; P=0.006). Nonfatal target-territory myocardial infarction (MI) was higher with native PCI (HR 2.12; P=0.029), as was repeat revascularization (HR 2.19; P=0.044). PCI-related MI occurred in 13 percent with native PCI and one percent with SVG PCI (HR 14.85; P=0.009). All-cause mortality did not differ (HR 1.59; P=0.472). SVG PCI produced significantly better one-year outcomes.
This meta-analysis of eight randomized clinical trials (RCT) compared no-touch (NT) vs conventional (CON) saphenous vein (SV) harvesting in coronary bypass surgery. At a 3.7-year follow-up, NT-SV harvesting showed significantly lower graft failure rates compared to CON-SV. However, mortality and major adverse cardiac events were similar between groups. NT-SV harvesting was associated with higher leg wound complications. The author’s conclusion was that NT-SV harvesting reduces graft failure but increases wound complications; thus, strategies to mitigate harvest-site complications are needed.
Sir Terence English, the pioneering cardiac surgeon who performed the United Kingdom’s first successful heart transplant in 1979, has died at the age of 93. His groundbreaking work helped Royal Papworth Hospital achieve an international reputation for heart transplantation and, later, heart-lung and lung transplants. In 1991, he was knighted for his contributions to surgery and medicine. Sir Terrence will be remembered for his commitment to surgical excellence and mentorship in cardiothoracic surgery, and as somebody who encouraged others to find their own passions.
This article examines both preclinical and clinical results in cardiac xenotransplantation, highlighting the ongoing challenges in achieving consistent and durable clinical graft survival. The authors discuss the relative value of preclinical nonhuman primate and human decedent transplant models to optimize patient cross-matching, immune suppression, postoperative monitoring, and graft survival.
The DECAF randomized clinical trial investigated whether caffeinated coffee influences the recurrence of atrial fibrillation (AF) after cardioversion. Two hundred patients with persistent AF were randomized to either continue consuming caffeinated coffee (≥1 cup daily) or abstain entirely for six months. AF or atrial flutter recurred in 47 percent of coffee drinkers compared to 64 percent of abstainers, corresponding to a 39 percent lower recurrence risk (HR 0.61; 95 percent CI 0.42–0.89; P = .01). Secondary analyses showed similar trends for AF alone. No differences were seen in adverse events. Contrary to longstanding assumptions, moderate caffeinated coffee intake was associated with a reduced risk of AF recurrence. Proposed mechanisms for this effect include adenosine receptor antagonism, anti-inflammatory effects, and enhanced physical activity.
While seasonal patterns suggest that cold weather influences the incidence of acute type A aortic dissection, the impact of subjective thermal stress on dissection risk remains poorly characterized. This retrospective multicenter study examined environmental triggers of acute type A aortic dissection in 548 German patients between 1996 and 2016. Subjective cold exposure, particularly perceived as windchill, significantly increased dissection odds by up to 50 percent, peaking three to four days before events. Elevated atmospheric pressure and low dew point also increased risk, while lower humidity showed modest protection. The acute temporal pattern suggests that cold-induced sympathetic activation, vasoconstriction, and blood pressure surges may precipitate dissection in vulnerable individuals. These interesting findings emphasize that perceived environmental stress outweighs ambient temperature in triggering acute aortic events, highlighting opportunities for targeted prevention during adverse weather conditions.
In this international randomized trial involving 2,124 thoracic surgery patients requiring one-lung ventilation, the authors compared high positive end-expiratory pressure (PEEP) with recruitment maneuvers (10 cm H2O) to standard low PEEP without recruitment (5 cm H2O). Despite improved oxygenation and lower driving pressures with the high-PEEP strategy, there was no significant reduction in postoperative pulmonary complications (53.6 percent vs 56.4 percent). High PEEP caused substantially more intraoperative hypotension and arrhythmias, whereas hypoxemia occurred more often with low PEEP. Postoperative outcomes, including mortality and extrapulmonary complications, were similar between the groups. These findings indicate that routine intraoperative lung-expansion strategies do not improve pulmonary outcomes in this setting, and PEEP selection should instead be individualized based on real-time gas-exchange and hemodynamic status.
This 10-year, single institution propensity-matched study investigated the outcomes of supervised resident-led emergency cardiac surgery compared to consultant-led procedures. Among 1,241 emergency cases, 364 matched pairs were analyzed, and overall outcomes were noted to be similar. Despite longer cardiopulmonary bypass times in consultant-led cases—possibly suggesting greater complexity—there were no significant differences in in-hospital mortality (13.7 percent vs 13.5 percent), major complications, or long-term survival up to 10 years. Subgroup analyses focusing on high-risk cases, emergent revascularization, infective endocarditis, and acute aortic syndromes confirmed comparable outcomes. The authors suggest that these findings validate structured training programs that progressively increase resident autonomy under supervision, addressing concerns about reduced training duration and working-hour restrictions. The study supports the safety and efficacy of resident involvement in high-stakes emergency cardiac surgery, demonstrating that appropriate supervision enables skill development without compromising patient outcomes.
This cross-sectional study compared the personality traits of 224 Dutch vascular surgeons, cardiothoracic surgeons, and interventional radiologists using the validated Big Five Inventory-2. While all specialists showed higher levels of open-mindedness, conscientiousness, extraversion, and agreeableness, along with lower levels of negative emotionality compared to the general population, notable differences emerged between the specialties. Cardiothoracic surgeons were found to be more agreeable than interventional radiologists, while vascular surgeons showed lower levels of negative emotionality. Facet-level analyses revealed distinctions in compassion, creative imagination, and assertiveness. These differences suggest that unique personality patterns exist even among professionals working within similar cardiovascular care pathways. Importantly, personality differences have been linked with surgical outcomes, clinical decision-making, and teamwork, and should be investigated further.