This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Journal and News Scan

Source: The Annals of Thoracic Surgery
Author(s): Vladimiro L. Vida, Lorenza Zanotto, Lucia Zanotto, Giovanni Stellin and the European Congenital Heart Surgeons Association (ECHSA) Study Group, Massimo Padalino, Georges Sarris, Eleftherios Protopapas, Carol Prospero, Christian Pizarro, Edward Woodford, Thomas Tlaskal, Hakan Berggren, Martin Kostolny, Ikenna Omeje, Boulos Asfour, Alexander Kadner, Thierry Carrel, Paul H. Schoof, Matej Nosal, Josè Fragata, Michał Kozłowski, Bohdan Maruszewski, Luca A. Vricella, Duke E. Cameron, Vladimir Sojak, Mark Hazekamp, Jukka Salminen, Ilkka P. Mattila, Julie Cleuziou, Patrick O. Myers, Viktor Hraska

Vida and colleagues retrospectively reviewed 111 left-sided reoperations after an arterial switch operation (ASO) across 17 ECHSA centers between 1975 and 2010. The authors found a low reoperation frequency of 1.4% after ASO. Initial diagnosis of D-transposition of the great arteries (D-TGA) was more common among patients who required reoperation than was diagnosis of double-outlet right ventricle TGA-type, however a greater percentage of the latter group encountered postoperative complications (5 of 12, versus 16 of 99). The majority of survivors were asymptomatic at last follow-up, with only 13% in New York Heart Association class II and only 3% in class III.

CME related to this article is available through The Annals' website.

Source: BioMed Central
Author(s): Policlinico University Hospital, University of Catania, Morgani Institute, Policlinico Giaccone, University of Palermo (Italy). Main Contact: Prof. Marcello Migliore.

We urgently need more answers for the patients affected by mesothelioma, a devastating diasese whose prognosis is 6-9 months from the diagnosis. We are now living the era of plateau of the epidemiology due to industrial use of amiantus of the last century. Furthermore, there are other etiology than asbestos in endemic areas, like for example the natural exposure to fluoro-edenite of certain regions of Japan and Sicily. We do need more informatinos to direct the difficult management of all these individuals and there are many ongoing studies where surgery is considered a valid option. This trial will compare the outcome of 2 groups: the first group will have a debulking surgery and hyperthermic intraoperative intrathoracic chemotherapy (HITHOC) with cisplatinum while the second group will receive talc pleurodesis alone. The primary outcomes measured will be length of hospital stay, quality of life, and long-term survival.

Source: World Journal for Pediatric and Congenital Heart Surgery
Author(s): Connor Patrick Callahan, MD, David Saudek, Amanda Shillingford, Sara Creighton, Garick Hill, William K Johnson, PhD, James Tweddell, Michael E. Mitchell, Ronald Woods

This single institution observational study compares clinical outcomes and resource utilization associated with two surgical approaches for single-stage repair of coarctation of the aorta and ventricular septal defect. Authors found that single-stage two-incision repair of both defects in appropriately selected patients may be associated with higher value of care compared to single-stage one incision repair.

Source: Annals of Thoracic Surgery
Author(s): Dhaval Chauhan, MD, Alexis K. Okoh, MD, Setri Fugar, MD, Rivandra Karanam, MD, David Baran, MD, Mark Zucker, MD, Magarita Camacho, MD, Mark J. Russo, MD

The authors queried the UNOS heart transplantation database to determine if LVAD device-related complications (DRCs) were associated with worse postoperative graft survival.  The 5 categories of DRCs were as follows:  device thrombosis, infection, device malfunction, life-threatening arrhythmias, and others.  

Results:  None of the 5 categories of DRCs was associated with worse graft survival on multivariate analysis.

Source: Journal of Thoracic and Cardiovascular Surgery
Author(s): Michael E. Halkos, Aaron Anderson, Jose Nilo G. Binongo, Anthony Stringer, Yi Lasanajak, Vinod H. Thourani, Omar M. Lattouf, Robert A. Guyton, Kim T. Baio, Eric Sarin, William B. Keeling, N. Renee Cook, Katherine Carssow, Alexis Neill, Kathryn E. Glas, John D. Puskas

In this study the authors randomized 142 patients within two separate treatment arms:  (1) Patients undergoing on-pump CABG were randomized to either a single- vs. double-clamp technique for proximals; (2)  patients undergiong OPCAB were randomized to either a Heartstring device or single clamp for proximals.  For all 4 treatment groups, the number of embolic HITS was assessed with transcranial doppler of the middle cerebral artery.


(1)  On-pump CABG:  The mean number of HITS in the single-clamp group was 10.0, while that for the double-clamp group was 16.0 (p=.10). (Although the difference was not significant, the treatment groups were rather small.)

(2)  OPCAB:  The mean number of HITS in the Heartstring group was 30.0, whereas that for the partial clamp group was 7.0 (p<.0001).  Thus, the Heartstring group had more than 4 times the embolic load by TCD.

Notably, neurocognitive outcomes were not different among the groups.

Source: News from around the web.
Author(s): Claire Vernon

Patient Care

Three more UK surgical centers will introduce heart transplants from non-heart beating donors. In the UK, this procedure is currently only performed at three hospitals, where it benefits patients such as this sports enthusiast.

The Montreal Heart Institute in Canada has a new surgical robot dedicated to CABG and mitral valve surgery.


Drugs and Devices

Neovasc Inc. released an update on the performance of its self-expanding mitral bioprosthesis, the TiaraTM valve, which is being implanted in several European and US centers as part of three parallel investigational programs.

The European Medicines Agency and the European Center for Disease Control and Prevention will host a meeting to discuss the threat of antimicrobial resistance and how they can support efforts to combat this threat.


Research, Trials, and Funding

Researchers from France analyzed data from the US Nurses’ Health Study II, finding a correlation between exposure to disinfectants and development of COPD.

Chinese researchers have published a case study on closing aortic anastomosis leaks with a transcatheter approach.

A study of a Swedish national database matched sibling pairs to further investigate the relationship between height and likelihood of venous thromboembolism.

Source: The Society of Thoracic Surgery
Author(s): Thomas D'Amico, Todd Demmy, Mark Onaitis, Shari Meyerson

Minimally Invasive Lobectomy for Lung Cancer is the latest installment in the Society’s webinar series on quality initiatives. The webinar features Drs Bill R. Burfeind Jr (moderator), Thomas A. D’Amico, Todd L. Demmy, Mark W. Onaitis, and Shari L. Meyerson.

Watch 47 minutes of the world's experts talking about this technique

Source: Daily Record
Author(s): Vicki Newman

The actor, who also starred in Goodfellas, passed away at a New Jersey hospital on Wednesday while undergoing surgery.

The star was having the operation after suffering a heart attack last week, but sadly died on the operating table. 

Source: Annals of Cardiothoracic Surgery
Author(s): Kunal D. Kotkar, Sameh M. Said, Joseph A. Dearani, Hartzell V. Schaff

This study details the short- and long-term outcomes for more than 3,000 patients who underwent septal myectomy for hypertrophic cardiomyopathy at the Mayo Clinic in Rochester, United States, from 1993 to 2016. In over 90% of severely symptomatic patients, relief of left ventricular outflow tract obstruction resulted in clinical improvement by at least two functional classes and reduced or eliminated symptoms of dyspnea, angina, and/or syncope.

The authors also outline outcomes for the transapical approach for basal obstruction with systolic anterior motion in 115 patients between 1993 and 2012, with all patients demonstrating postoperative gradient relief without the complication of an apical aneurysm or ventricular septal defect. These results emphasize that excellent outcomes can result from myectomy performed in experienced centers, with early mortality for isolated septal myectomy being less than 1%. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Takayuki Abe, Kiyozo Morita, Gen Shinohara, Kazuhiro Hashimoto, Masako Nishikawa

Remote perconditioning at the hindlimb and terminal warm blood cardioplegia provide synergistic cardioprotection for cardioplegic arrest in an in vivo piglet model.