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Giuseppe Raffa

Giuseppe Maria Raffa, M.D.

Cardiac Surgery and Heart Transplantation Unit, Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT)
via Tricomi n 5
Palemro  90127
Italy
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Role: 
Surgeon - Cardiothoracic

Background

Erasmus Program, Imperial College of London (2001)
Messina University Medical School (M.D. 2003)
Italian Medical Board (2003)
Pavia University Cardiac Surgery Residency (2003-2008)
Karolinska Stockholm University Cardiac Fellow (2007-2008)
The Salam Centre for Cardiac Surgery, Emergency NGO, Khartoum, Sudan (2009)
Cardiac Surgery Unit, Istituto Clinico Humanitas,Humanitas Mirasole S.p.A. (2009 – 2013)
Cardiac Surgery Fellowship , IRCCS-ISMETT, University of Pittsburgh Medical Centre (2013-2015)
Visiting research fellow, Presbyterian Hospital- Mc Gowan Institute, University of Pittsburgh Medical Centre (2015)
Attending of Cardiac Surgery, IRCCS-ISMETT, University of Pittsburgh Medical Centre (2016-to date)

Other Interests

  • The Society of Thoracic Surgeons (ID: 261160)
  • The Extracorporeal Life Support Organization (ELSO) (#2144223)                             
  • Italian Society of Cardiac Surgery
  •  Cardio-Thoracic Surgery Network
  • Member of Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO)
  • Member of Società Italiana di Cardiologia (SIC)

 

Research

  1. Clinical relevance of the International Society for Heart and Lung Transplantation consensus classification of primary graft dysfunction after heart transplantation: Epidemiology, risk factors, and outcomes. Sabatino Mario, Vitale Giuseppe, Manfredini Valentina, Masetti Marco, Borgese Laura, Raffa G, Loforte Antonio, Suarez Sofia Martin, Falletta Calogero, Marinelli Giuseppe, Clemenza Francesco, Grigioni Francesco, Potena Luciano (2017). THE JOURNAL OF HEART AND LUNG TRANSPLANTATION, ISSN: 1053-2498, doi: http://dx.doi.org/10.1016/j.healun.2017.02.014
  2. Training in Coronary Artery Bypass Surgery: Tips and Tricks of the Trade. Giuseppe Maria Raffa, Pietro Giorgio Malvindi, Mariusz Kowalewski, Fabrizio Sansone, Lorenzo Menicanti. Seminars in Thoracic and Cardiovascular Surgery (2017), http://dx.doi.org/doi: 10.1053/j.semtcvs.2017.01.015.
  3. Aortic surgery in Marfan patients with severe pectus excavatum. Raffa GM, Kowalewski M, Malvindi PG, Bertani A, Romano G, Sciacca S, Turrisi M, Armaro A, Stringi V, Montalbano G, Mattiucci G, Follis F, Pilato M. J Cardiovasc Med (Hagerstown). 2017 May;18(5):305-310.
  4. Preserving the left subclavian artery patency in challenging proximal neck during thoracic endovascular aortic repair. Settepani F, Raffa GM, Malvindi PG, Tarelli G, Brambilla G, Pedicini V. J Cardiovasc Med (Hagerstown). 2017 May;18(5):374-377.
  5. Migrants crossing the Mediterranean Sea: an opportunity or a duty? Raffa GM, Martucci G, Panarello G. Intensive Care Med. 2017 Mar 2. doi:10.1007/s00134-017-4726-z.
  6. Three-dimensional parametric modeling of bicuspid aortopathy and comparison with computational flow predictions. Pasta S, Gentile G, Raffa GM, Scardulla F, Bellavia D, Luca A, Pilato M, Scardulla C. Artif Organs. 2017 Feb 10. doi:10.1111/aor.12866.
  7. Antihypertensive Treatments In Patients Affected By Aortic Valve Stenosis. Poggio P, Folesani G, Raffa GM, Songia P, Valenti V, Myasoedova V, Parolari A. Curr Pharm Des. 2016 Nov 23
  8. Clinical Safety and Effectiveness of Endoaortic as Compared to Transthoracic Clamp for Small Thoracotomy Mitral Valve Surgery: Meta-Analysis of Observational Studies. Kowalewski M, Malvindi PG, Suwalski P, Raffa GM, Pawliszak W, Perlinski D, Kowalkowska ME, Kowalewski J, Carrel T, Anisimowicz L. Ann Thorac Surg. 2016 Oct 17. pii: S0003-4975(16)31140-7. doi: 10.1016/j.athoracsur.2016.08.072. Review.
  9. Robotic mitral repair with sliding leaflet valvuloplasty and remodelling partial annuloplasty. Murashita T, Raffa GM, Wei LM, Badhwar V.  Multimed Man Cardiothorac Surg. 2016 Sep 28;2016.
  10. Computational fluid dynamics of the ascending aorta before the onset of type A aortic dissection. Malvindi PG, Pasta S, Raffa GM, Livesey S. Eur J Cardiothorac  Surg. 2016 Sep 15.
  11. From Small Coronary Artery Aneurysm to Giant Left Ventricle Aneurysm. Sciacca S., Raffa GM, Gentile G., Pilato M. MEDICAL PRINCIPLES AND PRACTICE, vol. 26, p. 87-89, ISSN: 1011-7571
  12. Meta-analysis of uninterrupted as compared to interrupted oral anticoagulation with or without bridging in patients undergoing coronary angiography with or without percutaneous coronary intervention. Kowalewski M, Suwalski P, Raffa GM, Słomka A, Kowalkowska ME, Szwed KA, Borkowska A, Kowalewski J, Malvindi PG, Undas A, Windyga J, Pawliszak W, Anisimowicz L, Carrel T, Paparella D, Lip GY. Int J Cardiol. 2016 Aug 4;223:186-194.
  13. Risk of stroke with "no-touch" – As compared to conventional off-pump coronary artery bypass grafting. An updated meta-analysis of observational studies. Kowalewski M, Suwalski P, Pawliszak W, Benetti F, Raffa GM, Malvindi PG, Carrel T, Paparella D, Anisimowicz L. Int J Cardiol. 2016 Aug 3;222:769-771.
  14. Heart transplant program at IRCCS-ISMETT: impact of mechanical circulatory support on pre- and post -transplant survival. Raffa GM, Di Gesaro G, Sciacca S, Tuzzolino F, Turrisi M, Falletta C, Minà C, Romano G, Vitale G, Panarello G, Clemenza F, Pilato M. Int J Cardiol. 2016 Sep 15;219:358-61
  15. PIWI-interacting RNA (piRNA) signatures in human cardiac progenitor cells. Vella S, Gallo A, Lo Nigro A, Galvagno D, Raffa GM, Pilato M, Conaldi PG. Int J Biochem Cell Biol. 2016 Apr 27;76:1-11.
  16. International Participation in The STS Database Improves Outcomes: Initial Italian Experience. Raffa GM, Luca A, Badhwar V, Pilato M. Ann Thorac Surg. 2015 September
  17. Cerebrovascular Events After No-Touch Off-Pump Coronary Artery Bypass Grafting, Conventional Side-Clamp Off-Pump Coronary Artery Bypass, and Proximal Anastomotic Devices: A Meta-Analysis. Pawliszak W, Kowalewski M, Raffa GM, Malvindi PG, Kowalkowska ME, Szwed KA, Borkowska A, Kowalewski J, Anisimowicz L. J Am Heart Assoc. 2016 Feb 18;5(2).
  18. Can multiple previous treatment-requiring rejections affect biventricular myocardial function in heart transplant recipients? A two-dimensional speckle-tracking study. Romano G, Raffa GM, Licata P, Tuzzolino F, Baravoglia CH, Sciacca S, Scardulla C, Pilato M, Lancellotti P, Clemenza F, Bellavia D. Int J Cardiol. 2016 Feb 3;209:54-56.
  19. Patients with bicuspid aortic valve are likely to receive an aortic valve prosthesis during prophylactic resection of their ascending aortic aneurysm. Raffa GM, Wu B, Pasta S, Morsolini M, Bellavia D, Romano G, Falletta C, Pietrosi A, Scardulla C, Pilato M. Int J Cardiol. 2016 Mar 1;206:97-100.
  20. Early Distal Remodeling after Elephant Trunk Repair of Thoraco-Abdominal Aortic Aneurysms. Raffa GM, Pasta S, Gentile G, Scardulla F, Wu B, D’Ancona G, Follis F, Pilato M. J Biomech. 2015 Dec 31
  21. Should pectus excavatum alter aortic root surgery in Marfan patients? A CT-scan guided surgical strategy through left anterior thoracotomy. Raffa GM, Gentile G, De Monte L, Pilato M. Seminars in Thoracic and Cardiovascular Surgery. Semin Thorac Cardiovasc Surg. 2015 Autumn;27(3):328-30.
  22. Your Results, Explained: Clarity Provided by Row Percentages vs Column Percentages. Althouse A. Raffa GM, Kormos R.  Ann Thorac Surg. 2016 Jan;101(1):15-7.
  23. Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters. Pasta S, Phillippi JA, Tsamis A, D'Amore A, Raffa GM, Pilato M, Scardulla C, Watkins SC, Wagner WR, Gleason TG, Vorp DA. Med Eng Phys. 2016 Feb;38(2):121-30.
  24. Safety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled trials involving 22 778 patients. Kowalewski M, Pawliszak W, Raffa GM, Malvindi PG, Kowalkowska ME, Zaborowska K, Kowalewski J, Tarelli G, Taggart DP, Anisimowicz L. Eur J Cardiothorac Surg. 2015 Nov 3
  25. Stanford Type-A Acute Retrograde Aortic Dissections: from Surgical to Endovascular Strategy? Follis F, Raffa GM, D'Ancona G, Amaducci A, Follis F. Artif Organs. 2015 Oct 30.
  26. An In Vitro Phantom Study on the Role of the Bird-Beak Configuration in Endograft Infolding in the Aortic Arch. Pasta S, Scardulla F, Rinaudo A, Raffa GM, D'Ancona G, Pilato M, Scardulla C. J Endovasc Ther. 2016 Feb;23(1):172-81.
  27. Off-Pump CABG Improves Short-Term Outcomes in High Risk Patients As Compared to On-Pump CABG: Meta-analysis. Kowalewski M, Pawliszak W, Malvindi PG; Bokszanski MP; Perlinski D; Raffa GM; Kowalkowska ME; Zaborowska K; Navarese EP; Kolodziejczak M; Kowalewski J; Tarelli G; Taggart DP; Anisimowicz L. J Thorac Cardiovasc Surg. 2016 Jan;151(1):60-77.e58.
  28. Biomechanical implications of excessive endograft protrusion into the aortic arch after thoracic endovascular repair. Rinaudo A, Raffa GM, Scardulla F, Pilato M, Scardulla C, Pasta S. Comput Biol Med. 2015 Nov 1;66:235-41
  29. How do I get my paper published? Insight from an EACTS luncheon. Raffa GM, Beyersdorf F. J Cardiovasc Med (Hagerstown). 2015 Aug 7.
  30. Recurrent ventricular tachycardia in a patient with continuous flow left ventricle assist device: Successful management with radiofrequency ablation and medical treatment. Romano G, Raffa GM, Ruggieri A, Sgarito G, Falletta C, Sciacca S, Pilato M, Clemenza F. Int J Cardiol. 2015 Jul 1;190:198-200.  
  31. Should Device Replacement Be the First Choice Strategy in Continuous-Flow Left Ventricle Assist Device Thrombosis? Analysis of 9 Events and Results after Endoventricular Thrombolysis. Raffa GM, D’Ancona G, Romano G, Falletta C, Sciacca S, Todaro C, Tuzzolino F, Pietrosi A, Amaducci A, Clemenza F, Scardulla C, Pilato M. Int J Cardiol. 2015 Jan 15;178:159-61.
  32. Commentary: the bird-beak stent-graft configuration: the end of aortic arch endograft collapse? Pasta S, Raffa GM, D'Ancona G, Pilato M. J Endovasc Ther. 2014 Dec;21(6):803-4.
  33. Thalassemia and Heart Surgery: A Case of Aortic Valve Repair after Endocarditis. Raffa GM, Mularoni A, Di Gesaro G, Vizzini G, Cipolla T, Pilato M. Ann  Thorac  Surgery. Ann Thorac Surg. 2015 Jan;99(1):e1-2.
  34. Systemic or Endoventricular Thrombolysis to Treat HeartWare Left Ventricle Assist Device Thrombosis: A Clinical Dilemma. Raffa GM, D’Ancona G, Sciacca S, Pietrosi A, Hernandez Baravoglia CM, Turrisi M, Romano G, Armaro A, Stringi V, Clemenza F, Pilato M. Artif Organs. Artif Organs. 2015 Jun;39(6):526-9.
  35. Chronic Stanford type A aortic dissection. Raffa GM, Pilato M, Armaro A, Ruperto C, Gentile G, Follis F. J Cardiovasc Med (Hagerstown). 2014 Aug 1.
  36. Cusp repair during aortic valve-sparing operation: technical aspects and impact on results. Settepani F, Cappai A, Raffa GM, Basciu A, Barbone A, Berwick D, Citterio E, Ornaghi D, Tarelli G, Malvindi PG. J Cardiovasc Med (Hagerstown). 2015 Apr;16(4):310-7.2014 Jun 27.
  37. Surgical treatment of systemic embolization by cardiac metastasis of lung cancer. Santise G, Raffa GM, Pilato M Asian Cardiovasc Thorac Ann. 2014 Nov;22(9):1103-5.
  38. Vascular access complications in patients with continuous-flow left ventricle assist device undergoing percutaneous invasive procedures: A word of caution. Raffa GM, D'Ancona G, Sciacca S, Santise G, Pilato G, Turrisi M, Clemenza F, Pilato M.  Int J Cardiol. 2014 Jul 1;174(3):768-9.
  39. David operation: single center 10-year experience. Malvindi PG, Cappai A, Basciu A, Raffa GM, Barbone A, Citterio E, Ornaghi D, Tarelli G, Settepani F. J Cardiovasc Surg (Torino). 2015 Aug;56(4):639-45.
  40. Analysis of postsurgical aortic false aneurysm in 27 patients. Malvindi PG, Cappai A, Raffa GM, Barbone A, Basciu A, Citterio E, Ornaghi D, Tarelli G, Settepani F. Tex Heart Inst J. 2013;40(3):274-80.
  41. Minimally invasive direct coronary artery bypass in the era of percutaneous coronary intervention. Raffa GM, Malvindi PG, Ornaghi D, Citterio E, Cappai A, Basciu A, Barbone A, Fossati F, Tarelli G, Settepani F. J Cardiovasc Med (Hagerstown). 2015 Feb;16(2):118-24.
  42. Hamartoma of mature cardiac myocytes: a cardiac tumour with preserved contractility. Raffa GM, Tarelli G, Balzarini L, Torta D, Monti L. Eur Heart J ardiovasc Imaging. 2013 Dec;14(12):1216.
  43. Conversion to sternotomy during sternal-sparing coronary artery surgery. Raffa GM, Settepani F. J Card Surg. 2013 Jul;28(4):386-7.
  44. Fish oil and postoperative atrial fibrillation: the Omega-3 Fatty Acids for Prevention of Post-operative Atrial Fibrillation (OPERA) randomized trial. Mozaffarian D, Marchioli R, Macchia A, Silletta MG, Ferrazzi P, Gardner TJ, Latini R, Libby P, Lombardi F, O'Gara PT, Page RL, Tavazzi L, Tognoni G; OPERA Investigators. JAMA. 2012 Nov 21;308(19):2001-11.
  45. Sutureless repair for postinfarction cardiac rupture: A simple approach with a tissue-adhering patch. Raffa GM, Tarelli G, Patrini D, Settepani F. J Thorac Cardiovasc Surg. 2013 Feb;145(2):598-9.
  46. Hamartoma of mature cardiac myocytes in adults and young: case report and literature review. Raffa GM, Malvindi PG, Settepani F, Melotti F, Monti F, Spaggiari P, Basciu A,Cappai A, Citterio E, Tarelli G. Int J Cardiol. 2013 Feb 20;163(2):e28-30.
  47. Mitral and aortic valve prosthetic endocarditis following percutaneous closure of mitral paravalvular leak. Malvindi PG, Raffa GM, Cappai A, Barbone A, Basciu A, Settepani F, Citterio E, Ornaghi D, Tarelli G, Vitali E. Ann Thorac Surg. 2013 Feb;95(2):e45-6.
  48. Left ventricular cleft. Cappai A, Malvindi PG, Raffa GM, Basciu A, Monti L. Eur Heart J Cardiovasc Imaging. 2013 Jan;14(1):14
  49. Left ventricular pseudoaneurysm following aortic valve prosthesis endocarditis. Malvindi PG, Ornaghi D, Tarelli G, Raffa GM. J Cardiovasc Med (Hagerstown). 2012 Jul;13(7):457-9.
  50. Postsurgical aortic false aneurysm: pathogenesis, clinical presentation and surgical strategy. Raffa GM, Malvindi PG, Ornaghi D, Basciu A, Barbone A, Tarelli G, Settepani F. J Cardiovasc Med (Hagerstown). 2013 Aug;14(8):593-6.
  51. 6 Months of "Temporary" Support by Levitronix Left Ventricular Assist Device. Barbone A, Malvindi PG, Sorabella RA, Cortis G, Tosi PF, Basciu A, Ferrara P, Raffa G, Citterio E, Settepani F, Ornaghi D, Tarelli G, Vitali E. Artif Organs. 2012 Jul;36(7):639-42.
  52. Bicuspidy does not affect reoperation risk following aortic valve reimplantation. Malvindi PG, Raffa GM, Basciu A, Citterio E, Cappai A, Ornaghi D, Tarelli G, Settepani F. Interact Cardiovasc Thorac Surg. 2012 Jun;14(6):717-20.
  53. Aortic valve replacement for paraprosthetic leak after transcatheter implantation. Raffa GM, Malvindi PG, Settepani F, Ornaghi D, Basciu A, Cappai A, Tarelli G. J Card Surg. 2012 Jan;27(1):47-51. Review article.
  54. Long-term patency of saphenous vein patch plasty for left main coronary artery ostial disease. Raffa GM, Gaeta R, Carlo P, Marcello S, Viganò M. J Card Surg. 2011 Nov;26(6):629.
  55. Giant left atrium syndrome. Raffa GM, Cappai A, Tarelli G. J Cardiovasc Med (Hagerstown). 2011 Oct;12(10):745-6.
  56. Incidence of neoplastic disease following lung transplantation: a 17-year single centre experience. Pellegrini C, Nicolardi S, Savasta M, Totaro P, Meloni F, Ippoliti G, Oggionni T, Raffa G, D'Armini AM, Viganò M. Transplant Proc. 2011 May;43(4):1156-8.
  57. Endothelin-1 and Brain Natriuretic Peptide plasma levels decrease after aortic surgery. Raffa GM, Jackson V, Liska J, Eriksson MJ, Caidahl K, Eriksson P, Cereceda AF. J Heart Valve Dis. 2010 Nov;19(6):724-30.
  58. Domino heart transplantation: long-term outcome of recipients and their living donors: single center experience. Raffa GM, Pellegrini C, Viganó M. Transplant Proc. 2010;42(9):3688-93.
  59. Aortic valve replacement by ministernotomy in redo patients with previous left internal mammary artery patent grafts. Gaeta R, Lentini S, Raffa G, Pellegrini C, Zattera G, Viganò M. Ann Thorac Cardiovasc Surg. 2010;16(3):181-6.
  60. Treatment of ascending aorta disease with Bentall-De Bono operation using a mini-invasive approach. Perrotta S, Lentini S, Rinaldi M, D'armini AM, Tancredi F, Raffa G, Gaeta R, Viganó M. J Cardiovasc Med (Hagerstown). 2008;9(10):1016-22.
  61. Minimally invasive video-assisted surgery for iatrogenic aortic root to right atrium fistula after incomplete percutaneous occlusion of patent foramen ovale: case report and review of the literature.  Raffa GM, C. Pellegrini, S. Lentini, S. Perrotta, F. Tancredi, R. Gaeta, M. Vigano´. J Cardiac Surgery. 2008;23:63-78.
  62. Minimally invasive aortic valve replacement complicated by disseminate zygomycosis  Raffa G, R. Gaeta, B. Castiglioni, B. Nocita, A. Viglio, M. Vigano´. Bollettino della Società Medico Chirurgica di Pavia. 2005;118(2):183-90 .

 

Practice Areas

  • Cardiac
  • Heart failure
  • Extracorporeal circulation
  • Mechanical circulatory assistance