ALERT!
This site is not optimized for Internet Explorer 8 (or older).
Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.
Hans Thyregod
Hans Gustav Hørsted Thyregod, MD, PhD, Consultant Adult & Pediatric Cardiac Surgeon
Background
University of Copenhagen (B. S. 2003)
School of Medicine, University of Copenhagen (M. D. 2006)
UCSF Pain Clinical Research Centre, Doris Duke Clinical Research Fellow (2003-2004)
Faculty of Health Sciences, University of Copenhagen (Ph. D. 2016)
Amager University Hospital, General Surgery and Internal Medicine Internships (2006-2007)
Gentofte University Hospital, Cardiothoracic Surgery Internship (2007)
Rigshospitalet, University of Copenhagen, Cardiothoracic Surgery Residency (2008-2017)
Rigshospitalet, University of Copenhagen, Cardiothoracic Surgery Research Fellow and Ph. D. fellow (2012-2016)
Rigshospitalet, University of Copenhagen, Cardiothoracic Surgery (adult and pediatric), Staff Surgeon (2017-May 2018)
Great Ormond Street Hospital for Children, London, U.K., Cardiothoracic Surgery Clinical Fellow, (June 2018-May 2019)
Rigshospitalet, University of Copenhagen, Consultant Cardiac Surgeon (adult and pediatric) (June 2019-now)
Other Interests
Congenital heart surgery
Grown-up congenital heart surgery
Aortic valve surgery
Transcatheter aortic valve implantation
Mitral valve surgery
Endocarditis surgery
Randomized clinical trials in heart surgery
Research
1: Jørgensen TH, Thyregod HGH, Savontaus M, Willemen Y, Bleie Ø, Tang M, Niemela M, Angerås O, Gudmundsdóttir IJ, Sartipy U, Dagnegaard H, Laine M, Rück A, Piuhola J, Petursson P, Christiansen EH, Malmberg M, Olsen PS, Haaverstad R, Sondergaard L, De Backer O; NOTION-2 investigators. Transcatheter Aortic Valve Implantation in Low-Risk Tricuspid or Bicuspid Aortic Stenosis: The NOTION-2 Trial. Eur Heart J. 2024 May 15:ehae331. doi: 10.1093/eurheartj/ehae331. Epub ahead of print. PMID: 38747246.
2: Kaur H, Tao B, Silverman M, Healey JS, Belley-Cote EP, Islam S, Whitlock RP, Devereaux PJ, Conen D, Bidar E, Kawczynski M, Ayala-Paredes F, Ayala-Valani LM, Sandgren E, El-Chami MF, Jørgensen TH, Thyregod HGH, Sabbag A, McIntyre WF. Recurrence of new-onset post-operative AF after cardiac surgery: detected by implantable loop recorders: A systematic review and Meta-analysis. Int J Cardiol. 2024 Jun 1;404:131930. doi: 10.1016/j.ijcard.2024.131930. Epub 2024 Mar 4. PMID: 38447764.
3: Thyregod HGH, Jørgensen TH, Ihlemann N, Steinbrüchel DA, Nissen H, Kjeldsen BJ, Petursson P, De Backer O, Olsen PS, Søndergaard L. Transcatheter or surgical aortic valve implantation: 10-year outcomes of the NOTION trial. Eur Heart J. 2024 Apr 1;45(13):1116-1124. doi: 10.1093/eurheartj/ehae043. PMID: 38321820; PMCID: PMC10984572.
4: Gröning M, Smerup MH, Munk K, Andersen H, Nielsen DG, Nissen H, Mortensen UM, Jensen AS, Bække PS, Bjerre J, Engholm M, Vejlstrup N, Juul K, Søndergaard EV, Thyregod HGH, Andersen HØ, Helvind M, De Backer O, Jøns C, Schmidt MR, Jørgensen TH, Sondergaard L. Pulmonary Valve Replacement in Tetralogy of Fallot: Procedural Volume and Durability of Bioprosthetic Pulmonary Valves. JACC Cardiovasc Interv. 2024 Jan 22;17(2):217-227. doi: 10.1016/j.jcin.2023.10.070. Epub 2023 Dec 20. PMID: 38127022.
5: Ahmad Y, Howard JP, Arnold AD, Madhavan MV, Cook CM, Alu M, Mack MJ, Reardon MJ, Thourani VH, Kapadia S, Thyregod HGH, Sondergaard L, Jørgensen TH, Toff WD, Van Mieghem NM, Makkar RR, Forrest JK, Leon MB. Transcatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials. Eur Heart J. 2023 Mar 7;44(10):836-852. doi: 10.1093/eurheartj/ehac642. PMID: 36660821.
6: Gröning M, Smerup MH, Nielsen DG, Nissen H, Munk K, Mortensen UM, Andersen H, Engholm M, Bjerre J, Vejlstrup N, Juul K, Søndergaard EV, Jensen AS, Jørgensen TH, Thyregod HGH, Andersen HØ, Jøns C, Helvind M, Sondergaard L. Temporal changes in the surgical management of patients with tetralogy of Fallot in Denmark: a nationwide cohort study. Eur J Cardiothorac Surg. 2023 Feb 3;63(2):ezad007. doi: 10.1093/ejcts/ezad007. PMID: 36617167.
7: Thyregod HGH, Ihlemann N. Measuring Transvalvular Aortic Pressure Gradients: Answering Questions or Asking New Ones? JACC Cardiovasc Interv. 2022 Sep 26;15(18):1849-1851. doi: 10.1016/j.jcin.2022.08.021. PMID: 36137688.
8: Buttar SN, Andersen HØ, Poulsen JB, Thyregod HGH. Inverted left atrial appendage mimicking a left atrial mass after surgical repair of an atrial septal defect: a case report. Eur Heart J Case Rep. 2022 Jun 21;6(7):ytac241. doi: 10.1093/ehjcr/ytac241. PMID: 35911491; PMCID: PMC9336571.
9: Jørgensen TH, Thyregod HGH, Ihlemann N, Nissen H, Petursson P, Kjeldsen BJ, Steinbrüchel DA, Olsen PS, Søndergaard L. Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement. Eur Heart J. 2021 Aug 7;42(30):2912-2919. doi: 10.1093/eurheartj/ehab375. PMID: 34179981; PMCID: PMC8347457.
10: D'Ascenzo F, Bruno F, Baldetti L, De Filippo O, Marengo G, Breviario S, Melillo F, Thyregod HGH, Thiele H, Sondergaard L, Popma JJ, Kodali S, Franchin L, Annaratone M, Marruncheddu L, Gallone G, Crimi G, La Torre M, Rinaldi M, Omedè P, Conrotto F, Salizzoni S, De Ferrari GM. Aortic valve replacement vs. balloon-expandable and self-expandable transcatheter implantation: A network meta-analysis. Int J Cardiol. 2021 Aug 15;337:90-98. doi: 10.1016/j.ijcard.2021.04.068. Epub 2021 May 8. PMID: 33974961.
11: Geisler BP, Jørgensen TH, Thyregod HGH, Pietzsch JB, Søndergaard L. Cost- effectiveness of transcatheter versus surgical aortic valve replacement in patients at lower surgical risk: results from the NOTION trial. EuroIntervention. 2019 Dec 6;15(11):e959-e967. doi: 10.4244/EIJ-D-18-00847. PMID: 31422922.
12: Søndergaard L, Ihlemann N, Jørgensen TH, Olsen PS, Thyregod HGH. Reply: Choosing the Right Valve. J Am Coll Cardiol. 2019 Jun 4;73(21):2785-2787. doi: 10.1016/j.jacc.2019.04.001. PMID: 31146827.
13: Søndergaard L, Ihlemann N, Capodanno D, Jørgensen TH, Nissen H, Kjeldsen BJ, Chang Y, Steinbrüchel DA, Olsen PS, Petronio AS, Thyregod HGH. Durability of Transcatheter and Surgical Bioprosthetic Aortic Valves in Patients at Lower Surgical Risk. J Am Coll Cardiol. 2019 Feb 12;73(5):546-553. doi: 10.1016/j.jacc.2018.10.083. PMID: 30732707.
14: Thyregod HGH, Ihlemann N, Jørgensen TH, Nissen H, Kjeldsen BJ, Petursson P, Chang Y, Franzen OW, Engstrøm T, Clemmensen P, Hansen PB, Andersen LW, Steinbruüchel DA, Olsen PS, Søndergaard L. Five-Year Clinical and Echocardiographic Outcomes From the NOTION Randomized Clinical Trial in Patients at Lower Surgical Risk. Circulation. 2019 Jun 11;139(24):2714-2723. doi: 10.1161/CIRCULATIONAHA.118.036606. Epub 2019 Feb 1. PMID: 30704298.
15: Panoulas VF, Francis DP, Ruparelia N, Malik IS, Chukwuemeka A, Sen S, Anderson J, Nihoyannopoulos P, Sutaria N, Hannan EL, Samadashvili Z, D'Errigo P, Schymik G, Mehran R, Chieffo A, Latib A, Presbitero P, Mehilli J, Petronio AS, Morice MC, Tamburino C, Thyregod HGH, Leon M, Colombo A, Mikhail GW. Female- specific survival advantage from transcatheter aortic valve implantation over surgical aortic valve replacement: Meta-analysis of the gender subgroups of randomised controlled trials including 3758 patients. Int J Cardiol. 2018 Jan 1;250:66-72. doi: 10.1016/j.ijcard.2017.05.047. PMID: 29169764.
16: Jørgensen TH, Thyregod HG, Tarp JB, Svendsen JH, Søndergaard L. Temporal changes of new-onset atrial fibrillation in patients randomized to surgical or transcatheter aortic valve replacement. Int J Cardiol. 2017 May 1;234:16-21. doi: 10.1016/j.ijcard.2017.02.098. Epub 2017 Feb 24. PMID: 28258844.
17: Ngo A, Hassager C, Thyregod HGH, Søndergaard L, Olsen PS, Steinbrüchel D, Hansen PB, Kjærgaard J, Winther-Jensen M, Ihlemann N. Differences in left ventricular remodelling in patients with aortic stenosis treated with transcatheter aortic valve replacement with corevalve prostheses compared to surgery with porcine or bovine biological prostheses. Eur Heart J Cardiovasc Imaging. 2018 Jan 1;19(1):39-46. doi: 10.1093/ehjci/jew321. PMID: 28158582.
18: Grønlykke L, Ihlemann N, Ngo AT, Thyregod HG, Kjaergaard J, Korshin A, Gustafsson F, Hassager C, Nilsson JC, Søndergaard L, Ravn HB. Measures of right ventricular function after transcatheter versus surgical aortic valve replacement. Interact Cardiovasc Thorac Surg. 2017 Feb 1;24(2):181-187. doi: 10.1093/icvts/ivw350. PMID: 27811168.
19: Søndergaard L, Steinbrüchel DA, Ihlemann N, Nissen H, Kjeldsen BJ, Petursson P, Ngo AT, Olsen NT, Chang Y, Franzen OW, Engstrøm T, Clemmensen P, Olsen PS, Thyregod HG. Two-Year Outcomes in Patients With Severe Aortic Valve Stenosis Randomized to Transcatheter Versus Surgical Aortic Valve Replacement: The All- Comers Nordic Aortic Valve Intervention Randomized Clinical Trial. Circ Cardiovasc Interv. 2016 Jun;9(6):e003665. doi: 10.1161/CIRCINTERVENTIONS.115.003665. PMID: 27296202.
20: Thyregod HG, Steinbrüchel DA, Ihlemann N, Ngo TA, Nissen H, Kjeldsen BJ, Chang Y, Hansen PB, Olsen PS, Søndergaard L. No clinical effect of prosthesis- patient mismatch after transcatheter versus surgical aortic valve replacement in intermediate- and low-risk patients with severe aortic valve stenosis at mid- term follow-up: an analysis from the NOTION trial. Eur J Cardiothorac Surg. 2016 Oct;50(4):721-728. doi: 10.1093/ejcts/ezw095. Epub 2016 Mar 22. PMID: 27005980.
21: Thyregod HG, Holmberg F, Gerds TA, Ihlemann N, Søndergaard L, Steinbrüchel DA, Olsen PS. Heart Team therapeutic decision-making and treatment in severe aortic valve stenosis. Scand Cardiovasc J. 2016 Jun;50(3):146-53. doi: 10.3109/14017431.2016.1148825. Epub 2016 Feb 25. PMID: 26825285.
22: Thyregod HGH, Steinbrüchel DA, Søndergaard L. Reply: Exploring the Role of Transcatheter Aortic Valve Replacement as the Preferred Treatment for Lower-Risk Patients. J Am Coll Cardiol. 2015 Oct 6;66(14):1638-1639. doi: 10.1016/j.jacc.2015.06.1345. PMID: 26429094.
23: Thyregod HG, Steinbrüchel DA, Søndergaard L. Reply: 1-Year Results From the NOTION Randomized Clinical Trial: Weighing Complications Against Functional Outcomes. J Am Coll Cardiol. 2015 Aug 25;66(8):980-1. doi: 10.1016/j.jacc.2015.06.1085. PMID: 26293774.
24: Olsen NT, De Backer O, Thyregod HG, Vejlstrup N, Bundgaard H, Søndergaard L, Ihlemann N. Prosthetic valve endocarditis after transcatheter aortic valve implantation. Circ Cardiovasc Interv. 2015 Apr;8(4):e001939. doi: 10.1161/CIRCINTERVENTIONS.114.001939. PMID: 25873728.
25: Thyregod HG, Steinbrüchel DA, Ihlemann N, Nissen H, Kjeldsen BJ, Petursson P, Chang Y, Franzen OW, Engstrøm T, Clemmensen P, Hansen PB, Andersen LW, Olsen PS, Søndergaard L. Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Severe Aortic Valve Stenosis: 1-Year Results From the All-Comers NOTION Randomized Clinical Trial. J Am Coll Cardiol. 2015 May 26;65(20):2184-94. doi: 10.1016/j.jacc.2015.03.014. Epub 2015 Mar 15. PMID: 25787196.
Printer-friendlyPractice Areas
- Cardiac
- Congenital