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Luis Tapias

Luis Felipe Tapias, MD

Mayo Clinic, Division of Thoracic Surgery
200 1st St SW
Mayo 12-34W
Rochester, MN  55905
United States
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Surgeon - Cardiothoracic


Universidad Industrial de Santander (M.D. 2010)
Saint Mary's Hospital -Waterbury, CT General Surgery Residency (2011-2012)
Massachusetts General Hospital General Surgery Residency (2012-2018)
Massachusetts General Hospital Thoracic Surgery Residency (2018-2020)


Research investigations

  1. Paez-Esteban AN, Orostegui-Arenas M, Valencia-Angel LI, Hernandez H, Tapias-Vargas LF, Reyes CI, Orozco LC. Validation of oscillometric ankle-brachial index compared to arterial duplex ultrasonography of lower extremities for peripheral arterial disease. Rev Colomb Cardiol 2010;17(4):157-66.


  1. Tapias-Vargas LF, Torres SA, Tapias-Vargas L, Santamaria CM, Valencia-Angel LI, Orozco-Vargas LC. Biological accidents among resident physicians from Bucaramanga, Colombia. Rev Colomb Cir 2010;25(4):290-9.


  1. Tapias-Vargas LF, Tapias-Vargas L, Torres SA, Vega A, Valencia-Angel LI, Orozco-Vargas LC. Biological accidents among medical students from Universidad Industrial de Santander, Bucaramanga, Colombia. Salud UIS 2010;42(3):192-200.


  1. Tapias-Vargas LF, Santamaria CM, Tapias-Vargas L, Tapias L. Lung wedge resections for histopathologic study: experience in Bucaramanga. Rev Colomb Cir 2011;26(1):32-43.


  1. Tapias LF, Morse CR. Minimally invasive Ivor Lewis esophagectomy after induction therapy yields similar early outcomes to surgery alone. Innovations (Phila) 2011;6(5):331-6.


  1. Tapias LF, Morse CR. A preliminary experience with minimally invasive Ivor Lewis esophagectomy. Dis Esophagus 2012;25(5):449-55.


  1. Tapias-Vargas LF, Santamaria-Ariza CM, Tapias-Vargas L, Tapias-Diaz L. Malignant solitary fibrous tumor of the pleura: Report of two cases. Cir Cir 2012;80:250-3.


  1. Tapias LF, Mino-Kenudson M, Lee H, Wright C, Gaissert HA, Wain JC, Mathisen DJ, Lanuti M. Risk factor analysis for the recurrence of resected solitary fibrous tumours of the pleura: a 33-year experience and proposal for a scoring system. Eur J Cardiothorac Surg 2013;44(1):111-7.


  1. Tapias LF, Muniappan A, Wright CD, Gaissert HA, Hayden D, Wain JC, Morse CR, Donahue DM, Mathisen DJ, Lanuti M. Short and long-term outcomes after esophagectomy for cancer in elderly patients. Ann Thorac Surg 2013;95(5):1741-8.


  1. Muniappan A, Tapias LF, Butala P, Wain JC, Wright CD, Donahue DM, Gaissert HA, Morse CR, Lanuti M, Mathisen DJ. Surgical therapy of pulmonary aspergillomas- a thirty-year North American experience. Ann Thorac Surg 2014;97(2):432-8.


  1. Tapias LF, Morse CR. Minimally invasive Ivor Lewis esophagectomy: description of a learning curve. J Am Coll Surg 2014;218(6):1130-40.


  1. Tapias LF, Mercier O, Ghigna MR, Lahon B, Lee H, Mathisen DJ, Dartevelle P, Lanuti M. Validation of a scoring system to predict recurrence of resected solitary fibrous tumors of the pleura. Chest 2015;147(1):216-23.


  1. Ren X, Tapias LF, Jank BJ, Lanuti M, Ott HC. Ex vivo non-invasive assessment of cell viability and proliferation in bioengineered whole organ constructs. Biomaterials 2015;52:103-12.


  1. Tapias LF, Gilpin SE, Ren X, Wei L, Fuchs BC, Tanabe KK, Lanuti M, Ott HC. Assessment of proliferation and cytotoxicity in a biomimetic three-dimensional model of lung cancer. Ann Thorac Surg 2015;100(2):414-21.


  1. Zhou H, Tapias LF, Gaissert HA, Muniappan A, Wright CD, Wain JC, Donahue DM, Morse CR, Mathisen DJ, Lanuti M. Lymph node assessment and impact on survival in video-assisted thoracoscopic lobectomy or segmentectomy. Ann Thorac Surg 2015;100(3):910-6.


  1. Ren X, Moser P, Gilpin SE, Okamoto T, Wu T, Tapias LF, Mercier F, Xiong L, Ghawi R, Mathisen DJ, Scadden D, Ott HC. Bioengineering human pulmonary vasculature on native extracellular matrix. Nat Biotechnol 2015;33(10):1097-102.


  1. Tapias LF, Mathisen DJ, Wright CD, Wain JC, Gaissert HA, Muniappan A, Lanuti M, Donahue DM, Morse CR. Outcomes with open and minimally invasive Ivor Lewis esophagectomy after neoadjuvant therapy. Ann Thorac Surg 2016;101(3):1097-103.


  1. Gilpin SE, Charest JM, Ren X, Tapias LF, Wu T, Evangelista-Leite D, Mathisen DJ, Ott HC. Regenerative potential of human airway stem cells in lung epithelial engineering. Biomaterials 2016;108:111-9.


  1. Desogere P*, Tapias LF*, Hariri LP, Rotile N, Rietz TA, Probst CK, Blasi F, Day H, Elliott J, Mino-Kenudson M, Weinreb P, Violette SM, Tager AM, Lanuti M, Caravan P. Imaging pulmonary fibrosis in vivo with a type I collagen-targeted positron emission tomography probe. Sci Transl Med 2017;9(384). pii: eaaf4696. *Co-first authors.


  1. Chen HH, Waghorn PA, Wei L, Tapias LF, Schuhle DT, Rotile NJ, Jones CM, Looby RJ, Zhao G, Elliott JM, Probst CK, Mino-Kenudson M, Lauwers GY, Tager AM, Tanae KK, Lanuti M, Fuchs BC, Caravan P. Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis. JCI Insight 2017;2(11). pii: 91506.


  1. Desogere P, Tapias LF, Rietz TA, Rotile N, Blasi F, Day H, Elliott J, Fuchs BC, Lanuti M, Caravan P. Optimization of a collagen-targeted positron emission tomography probe for molecular imaging of pulmonary fibrosis. J Nucl Med 2017;58(12):1991-6.


  1. Tapias LF, Morse CR, Mathisen DJ, Gaissert HA, Wright CD, Allan JS, Lanuti M. Surgical management of esophageal epiphrenic diverticula: A transthoracic approach over four decades. Ann Thorac Surg 2017;104(4):1123-30.


  1. Tapias LF, Shih A, Mino-Kenudson M, Muniappan A, Gaissert HA, Lanuti M, Mathisen DJ, Ott HC. Programmed death ligand 1 and CD8+ immune cell infiltrates in resected primary tracheal malignant neoplasms. Eur J Cardiothorac Surg 2019;55(4):691-8.


  1. Tapias L, Tapias LF, Moonsamy P, Lanuti M, Gaissert HA, Wright CD, Muniappan A, Mathisen DJ, Morse CR. Impact of radial margin status after esophagectomy for adenocarcinoma. J Gastrointest Surg 2020;24(5):983-90.


  1. Tapias LF, Wright CD, Lanuti M, Muniappan A, Deschler D, Mathisen DJ. Hyperbaric oxygen therapy in the prevention and management of tracheal and oesophageal anastomotic complications. Eur J Cardiothorac Surg 2020;57(6):1203-9.


  1. Tapias LF, Rogan T, Wright CD, Mathisen DJ. Pregnancy-associated idiopathic laryngotracheal stenosis: presentation, management and results of surgical treatment. Eur J Cardiothorac Surg 2021;59(1):122-29.


  1. Tapias LF, Mino-Kenudson M, Choy E, Kem M, Muniappan A, Gaissert HA, Wright CD, Ott HC, Mathisen DJ, Lanuti M. Programmed death ligand 1 and immune cell infiltrates in solitary fibrous tumors of the pleura. Ann Thorac Surg 2021;112(6):1862-9.


  1. Tapias LF, Lanuti M, Wright CD, Hron TA, Ly A, Mathisen DJ, Ott HC. COVID-19 related post-intubation tracheal stenosis: early experience with surgical treatment. Ann Surg 2022;275(1):e271-3.


  1. Quiroga-Centeno AC, Bautista-Parada IR, Tapias LF, Gomez-Ochoa SA. Primary esophageal non-Hodgkin’s lymphoma: demographics, clinical characteristics, histopathologic types, and survival in 179 patients from the SEER program and systematic review of the literature. Esophagus 2021;18(4):734-42.



Other peer-reviewed publications


  1. Tapias LF, Tapias L, Torres SA. Biological accidents among medical students. Salud UIS 2007;39(3):183-189.


  1. Tapias L, Tapias-Vargas LF, Tapias-Vargas L. Primary cutaneous inoculation tuberculosis in a healthcare worker as a result of a surgical accident. Int J Dermatol 2008;47:833-835.


  1. Tapias L, Tapias-Vargas LF, Tapias-Vargas L. Complications of tube thoracostomy. Rev Colomb Cir 2009;24(1):46-55.


  1. Aldana M, Tapias-Vargas LF. Thoracic trauma in pediatrics: general overview. Medicas UIS 2009;22:55-65.


  1. Tapias L, Tapias-Vargas L, Tapias-Vargas LF. Diaphragmatic hernias: clinical and surgical challenge. Rev Colomb Cir 2009;24(2):95-105.


  1. Tapias-Vargas L, Tapias-Vargas LF, Tapias L. Myasthenia gravis and the thymus: past, present and future. Rev Colomb Cir 2009;24(4):269-82.


  1. Tapias-Vargas LF, Santamaria CM, Tapias-Vargas L, Tapias L. Terminal ileum and cecum perforation caused by intestinal tuberculosis in an HIV-positive patient. Rev Colomb Cir 2010;25(4):332-40.


  1. Tapias-Vargas L, Tapias-Vargas LF, Tapias L, Garcia ME, Mantilla JC, Garcia E. Primary adenoid cystic carcinoma of the lobar bronchus: case report. Rev Chil Cir 2011;63(1):73-5.


  1. Messa-Botero OA, Romero-Rojas AE, Chinchilla Olaya SI, Díaz-Pérez JA, Tapias-Vargas LF. Primary malignant solitary fibrous tumor/hemangiopericytoma of the parotid gland. Acta Otorrinolaringol Esp 2011; 62(3):242-5.


  1. Guyette JP, Gilpin SE, Charest JM, Tapias LF, Ren X, Ott HC. Perfusion decellularization of whole organs. Nat Protoc 2014;9(6):1451-68.


  1. Tapias LF, Lanuti M. Solitary fibrous tumors of the pleura: review of the literature with up-to-date observations. Lung Cancer Management 2015;4(4):169-79.


  1. Colaianni CA, Tapias LF, Cauley R, Sheridan R, Schulz JT, Goverman J. Injuries caused by explosion of electronic cigarette devices. Eplasty 2016;16:ic9.


  1. Feins EN, Jassar AS, Tapias LF, Isselbacher EM, Sundt TM. Extra-anatomic bypass of a complex adult coarctation. Ann Thorac Surg 2018;106(3):e151-4.


  1. Tapias LF, Campbell J, Rosenfield K, D’Alessandro DA. Pseudoaneurysm of the left main coronary artery: A complication of orbital atherectomy. Catheter Cardiovasc Interv 2018;92(3):507-10.



Review articles

  1. Tapias LF, Ott HC. Decellularized scaffolds as a platform for bioengineered organs. Curr Opin Organ Transplant 2014;19(2):145-52.


  1. Tapias LF, Ott HC, Mathisen DJ. Complications following carinal resections and sleeve resections. Thor Surg Clin 2015;25(4):435-47.


  1. Tapias LF, Mathisen DJ. Prevention and management of complications following tracheal resections – lessons learned at the Massachusetts General Hospital. Ann Cardiothorac Surg 2018;7(2):237-43.


Book chapters

  1. Tapias LF, Morse CR. Minimally invasive esophagectomy. In: Cameron JL and Cameron A, eds. Current Surgical Therapy, 11th edition.
  2. Tapias LF, Wright CD. Non-neoplastic disorders of the mediastinum. In: Grippi MA et al, eds. Fishman’s Pulmonary Diseases and Disorders, 6th edition.
  3. Tapias LF, Allen MS. Chest wall tumors. In: Sellke F, del Nido PJ, Swanson SJ, eds. Sabiston and Spencer Surgery of the Chest, 10th edition. (In Press)
  4. Tapias LF. Epiphrenic diverticulum repair. In: Colson Y, Morse C, eds. Massachusetts General Hospital Illustrated Tips and Tricks in Thoracic Surgery. (In Press)
  5. Predina JD, Tapias LF. Tracheal resection and reconstruction. In: Louis C, Luc JGY; Thoracic Surgery Residents Association, eds. TSRA Operative Dictations in Cardiothoracic Surgery, 2nd edition.


Letters to the editor

  1. Tapias LF, Lanuti M. Response to “Tapias-Score for predicting recurrences in resected solitary fibrous tumor of the pleura: controversial points and future perspectives”. Chest 2015;147(3):e116-7.
  2. Tapias LF, Lanuti M. Better prognostic models may result in improved patient selection for adjuvant therapies after complete resection of solitary fibrous tumors of the pleura. J Thorac Oncol 2015;10(7):e61.


Invited commentaries

  1. Tapias LF, Molena D. Commentary: To ignore evil is to become an accomplice to it: predicting malignancy in mediastinal lymph nodes. J Thorac Cardiovasc Surg 2020;159(6):2510-1.

Practice Areas

  • Thoracic
  • Minimally Invasive
  • Robotic
  • VATS
  • Thoracic
  • Chest wall
  • Diaphragm
  • Lung
  • Esophagus
  • Mediastinum
  • Pleura
  • Trachea and bronchi
  • Benign disease
  • Cancer
  • Infection
  • Education