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Cerebral oxygen delivery is reduced in newborns with congenital heart disease
MRI assessment of cerebral blood flow and calculated cerebral oxygen delivery were compared between neonates with congenital heart disease and normal controls. Although cerebral blood flow was similar between the groups, oxygen delivery was over 30% lower in neonates with congenital heart disease, primarily because of arterial desaturation. These findings may influence the timing of repair of congenital heart disease.