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Does Surgery Improve Survival of Patients with Malignant Pleural Mesothelioma?: A Multicenter Retrospective Analysis of 1365 Consecutive Patients

Monday, February 24, 2014

Submitted by

Mark Ferguson

Source

Source Name: Journal of Thoracic Oncology

Source URL: http://journals.lww.com/jto/Abstract/2014/03000/Does_Surgery_Improve_Survival_of…

Author(s)

Bovolato, Pietro; Casadio, Caterina; Billè, Andrea; Ardissone, Francesco; Santambrogio, Luigi; Ratto, Giovanni Battista; Garofalo, Giuseppe; Bedini, Amedeo Vittorio; Garassino, Marina; Porcu, Luca; Torri, Valter; Pastorino, Ugo

A group of 1365 pts from 6 institutions was retrospectively reviewed for outcomes after palliative treatment, chemotherapy alone, pleurectomy/decortication (P/D), or extrapleural pneumonectomy (EPP). Multivariable analysis identified age <70, epithelial histology, and chemotherapy as independent predictors of improved survival. In patients with all 3 favorable characteristics, median survival with or without P/D or EPP was similar.