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Epigenetics in Ascending Thoracic Aortic Aneurysm and Dissection

Tuesday, September 11, 2018

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Adeline Boileau, Mark E. Lindsay, Jean-Baptiste Michel, Yvan Devaux

In this review article, the authors focus on epigenetic regulation of gene expression, including the role of histone methylation and acetylation, deoxyribonucleic acid methylation, and noncoding ribonucleic acids in the pathogenesis of thoracic aortic aneurysms (TAA) and ascending aortic dissection (AAD). They provide a translational perspective, presenting recent data that motivate the evaluation of the potential of epigenetics to diagnose TAA and prevent ascending aortic dissection AAD.


Fascinating topic from three separate centres in Europe and North America, the free full text link in Britain is at present The periodical according to PubMed is Aorta (StaMford) confusing us Europeans even more between CONN (M) and CA (N), is this a synonym to TTCVS? The variation in the links and toponyms can be confusing........Well spotted as an article though, good read and thank you Emily.

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