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Minimally invasive coronary bypass versus percutaneous coronary intervention for isolated complex stenosis of the left anterior

Tuesday, May 10, 2022

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Nirav C. Patel, MD Jonathan M. Hemli, MD Karthik Seetharam, MD Varinder P. Singh, MD S. Jacob Scheinerman, MD Luigi Pirelli, MD

Retrospective review (propensity-matched) comparing patients undergoing PCI vs minimally invasive CABG for complex LAD lesions.
Overall 9-year survival was not significantly different between patient groups both before and after propensity matching. Midterm mortality in the matched minimally invasive direct coronary artery bypass group was low, irrespective of patient risk profile. By contrast, advanced age (hazard ratio, 1.10; P = .012) and obesity (hazard ratio, 1.09; P = .044) predicted increased late death after drug-eluting stent percutaneous coronary intervention among matched patients. Patients who underwent minimally invasive direct coronary artery bypass were significantly less likely to require repeat left anterior descending revascularization than those who had percutaneous coronary intervention, both before and after propensity matching. Smaller stent diameter in drug-eluting stent percutaneous coronary intervention was associated with increased left anterior descending reintervention (hazard ratio, 3.53; P = .005).

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