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Results of the baseline positron emission tomography can customize therapy of localized esophageal adenocarcinoma patients who achieve a clinical complete response after chemoradiation

Wednesday, October 30, 2013

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A. Suzuki, L. Xiao, T. Taketa, K. Sudo, R. Wadhwa, M. A. Blum, H. Skinner, R. Komaki, B. Weston, J. H. Lee, M. S. Bhutani, D. C. Rice, D. M. Maru, J. Erasmus, S. G. Swisher, W. L. Hofstetter, and J. A. Ajani

This single-center study analyzed outcomes for 323 pts with esophageal adenocarcinoma who achieved a clinical CR after chemoradiotherapy to determine the prognostic value of pretreatment PET.  Patients with an SUV >6 faired better with induction therapy and resection compared to definitive chemoradiotherapy.  Those with an SUV <6 did equally well with either treatment regimen.  PET SUV may facilitate determining whether bimodality or trimodality is optimal for patients with esophageal adenocarcinoma. 

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