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Safety and Efficacy of Stereotactic Body Radiotherapy for Stage I Non-Small-Cell Lung Cancer in Routine Clinical Practice: A Patterns-of-Care and Outcome Analysis

Thursday, July 25, 2013

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Source Name: Journal of Thoracic Oncology


Guckenberger, Matthias; Allgäuer, Michael; Appold, Steffen; Dieckmann, Karin Ernst, Iris; Ganswindt, Ute; Holy, Richard; Nestle, Ursula; Nevinny-Stickel, Meinhard; Semrau, Sabine; Sterzing, Florian; Wittig, Andrea; Andratschke, Nicolaus

A retrospective analysis of SBRT in 13 institutions over a 10 year interval was conducted on outcomes in 582 pts with Stage I NSCLC.  At 3 years, freedom from local recurrence was 80% and overall survival was 47%.  The biological dose was the most important determinant of outcomes.  With higher effective dosing, freedom from local recurrence was 92% and overall survival was 62%. 

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