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Surgical Treatment for Ischemic Heart Failure (STICH) Trial
The STICH trial compares medical therapy to medical therapy + CABG for ischemic cardiomyopathy. In this study of over 1,200 there were 462 deaths during a median f/u period of nearly 5 years. CABG reduced the risk of sudden death and death due to pump failure; overall cardiovascular death was reduced by CABG but not significantly (p=0.09). There was a substantial early increase in mortality in pts undergoing CABG; the protective effects of CABG were evident primarily after 2 years.