A latge RCT of the first myosin inhibitor in severe chronic heart failure: somewhat difficult to interpret results, as deaths were slightly higher in the intervention group while there was no 'significant' benefit in cardiovascular deaths.
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Cardiac - Other
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery: A Meta-Analysis
October 26, 2020
Within the limitations of a meta-analysis, a useful work advancing that PCI may have a hitherto masked or hidden mortality
October 4, 2020
The authors are concerned about the 'deaths at home' having the greatest contribution to the excess of acute cardiovascular deaths in that period of the recent epidemic, AND LOCKDOWN in England and Wales.
May 23, 2020
a readable review that advances the position that Adolphe Quetelet's formula is now clinically obsolete
Graduated Compression Stockings as Adjuvant to Pharmaco-Thromboprophylaxis in Elective Surgical Patients (GAPS Study): Randomised Controlled Trial
May 15, 2020
A medium-sized RCT from the Imperial College. The research question are of interest for all cardiovascular, thoracic, and general surgeons as well as all healthcare professionals.
A New Role for the Aldosterone/Mineralocorticoid Receptor Pathway in the Development of Mitral Valve Prolapse
May 11, 2020
Interesting hypothesis in a rodent model of myxomatous degeneration.
April 25, 2020
A timely article addressing common questions related to the COVID pandemic, particularly regarding preoperative decision-making for pediatric/congenital heart surgery.
April 13, 2020
Topical review on the epidemic in Britain, with a number of observations that relate to the cardiothoracic surgeons and all healthcare professionals: -The assertion that the National Health Service in Britain was overrun PRIOR to the pandemic. -The assertion that acute angina is now being undertreated.
March 26, 2020
In a cohort of 416 patients hospitalized with COVID-19, nearly 20% had elevated troponins indicating myocardial injury. These patients also had a host of other serum and radiographic abnormalities, were older, had more comorbidities, and more often required ventilatory support. Their mortality rate was 51% compared to 4.5% for other hospitalized pa
March 1, 2020
A very easy-to-read editorial that digests a manuscript on the IMPROVE study.