A short and readable commentary on monoclonal antibodies and dyslipidaemias, particularly on FOURIER, SPIRE and ODYSSEY trials
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Cardiac - Physiology
April 29, 2017
A succinct update relevant to all arrhythmia and heart failure surgeons. The concept of atrial cardiomyopathy is particularly stimulating.
Extracardiac Signs of Fluid Overload in the Critically Ill Cardiac Patient: A Focused Evaluation Using Bedside Ultrasound
January 31, 2017
Appropriate perioperative fluid management is of increasing interest for the team caring for the critically ill cardiac patient as fluid overload has been shown to have negative effects on organ function.
Baseline Immunoglobulin E Levels as a Marker of Doxorubicin- and Trastuzumab-Associated Cardiac Dysfunction
November 1, 2016
An interesting case series of cardiotoxicity of modern chemotherapy attempting to elucidate mechanisms of heart failure.
How Does Mitral Valve Repair Fail in Patients With Prolapse?—Insights From Longitudinal Echocardiographic Follow-Up
October 31, 2016
This single institution study explored the frequency and time course of failure of mitral valve repair for MR caused by prolapse using longitudinal echocardiography. Recurrent MR developed in 49 (5.7%) patients at a mean of 3.1 years; 6 had prolapse and 43 did not. Severe MS occurred in 3. Reoperation was performed in 21 patients, and was most c
Potassium and Magnesium Supplementation do not protect against Atrial Fibrillation after Cardiac Operation: a Time-Matched Analysis.
September 27, 2016
In this single institution retrospective study of postoperative cardiac surgery patients, serum potassium and magnesium levels at times when postoperative atrial fibrillation (POAF) occured were compared with levels in patients who did not experience POAF. The incidence of POAF was 37%, and was associated with increasing magnesium levels.
August 2, 2016
Physiologic effects of pulmonary endarterectomy (PEA) for chronic thromboembolic disease (CTED) were studied 1 year postop. PEA resulted in improved RV stroke volume response, heart rate response, and ventilatory efficiency related to exercise.
Donor Troponin and Survival After Cardiac Transplantation. An Analysis of the United Network of Organ Sharing Registry
June 25, 2016
A large retrospective study of the UNOS database advances that elevated troponin I in selected cardiac donors is NOT associated with various adverse events. The conclusion is likely to stimulate heated discussions.
Ventricular fibrogenesis activity assessed by serum levels of procollagen type III N-terminal amino peptide during the staged Fontan procedure
May 5, 2016
The authors measured serum amino-terminal procollagen III (PIII) as a marker of myocardial fibrogenesis in patients undergoing the Fontan procedure for single ventricle circulation and in controls. Patients with single venticle circulation had elevated PIII levels compared to controls. Staged Fontan elements successively reduced PIII levels. The
March 31, 2016
A commentary and follow-up comment on last year's ERICCA and RIPHeart- related publications in the NEJM.