Doug Mathisen reflects on his three decades of practice in a new interview that was filmed at the 2016 SCTS Annual Meeting in Birmingham, United Kingdom.
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Doubling of 30-Day Mortality by 90 Days After Esophagectomy: A Critical Measure of Outcomes for Quality Improvement
January 12, 2016
30-day and 90-day mortality rates were compared using information from the National Cancer Data Base 2007-2011. Among nearly 16,000 esophagectomies, the 30-day mortality rate was 4.2% and the 90-day rate was 8.9%. 90-day mortality was uniquely associated with tumor location, tumor stage, and receipt of neoadjuvant therapy.
Peroral Endoscopic Myotomy for Esophageal Achalasia: Outcomes of the First 100 Patients With Short-term Follow-up
December 23, 2015
Intermediate term results of a single institution experience with POEM for management of achalasia are reported for the first 100 cases. Most patients were women (59%) and the overall mean age was 48 years. POEM was successfully completed in 94 pts and without complications. Clinical success was declared in 94.5%, although pH studies documented ab
Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 1988–2012: A Single-institution, High-volume Experience in China
December 23, 2015
This longitudinal review of single institution experience with GEJ adenocarcinomas identified time-related trends. The proportion of GEJ tumors compared to all esophageal cancers increased from 22% to 36%. GERD increased from 7% to 11%. An increased in GERD was associated with an increased in the prevalance of Seiwert I tumors. There was a signi
Long-term Quality of Life and Risk Factors for Recurrence After Laparoscopic Repair of Paraesophageal Hernia
May 21, 2015
This prospective observational study followed 111 patients for 3 years after laparoscopic repair of a type III paraesophageal hernia. QOL improved at all postoperative time intervals from 28.5 preop to about 10. The radiographic recurrence rate was 27% at 1 year. Hernias involving most of the stomach were more likely to recur than smaller hernias.
May 17, 2015
In this population-based cohort study with 1044 patients who underwent esophagectomy for esophageal cancer between 1987 and 2010 in Sweden, the researchers found that a higher number of lymph nodes removed did not affect mortality in any specific stage.
Laparoscopic Repair of Very Large Hiatus Hernia With Sutures Versus Absorbable Mesh Versus Nonabsorbable Mesh: A Randomized Controlled Trial
January 10, 2015
This study investigated repair methods for large hiatal hernias randomized to suture only vs absorbable mesh vs nonabsorbable mesh. The design was randomized, double blind. At 12 mos the recurrence rate was 21%, with no difference among the groups. Postoperative symptoms were different among the groups, but these differences were judged to be of s
Systematic Review of the Impact of Surgical Harm on Quality of Life After General and Gastrointestinal Surgery
November 16, 2014
This article systematically reviewed the impact of surgical adverse events (SAEs) on quality of life after major GI surgery. The mean difference in QOL between pts with and without SAEs was highest for esophagectomy (0.14; scale 0 to 1), while results for antireflux surgery were mixed.
November 5, 2014
Long-term QOL outcomes were assessed in a single institution cohort of 63 patients undergoing colon interposition after esophagectomy. 48% of pts had a vagal sparing operation, and resection was performed for cancer in the majority of the pts. Followup median was 13 yrs. Mean SF36 scores were above the published average and GI QOL was 3 out of 4.
Surgery Alone Versus Chemoradiotherapy Followed by Surgery for Stage I and II Esophageal Cancer: Final Analysis of Randomized Controlled Phase III Trial FFCD 9901
August 9, 2014
This randomized trial involving 30 centers in France compared outcomes after induction chemoradiotherapy followed by resection to resection alone for stage I or II esophageal cancer. The R0 resection rate was similar between the groups. Postoperative mortality was higher in the induction therapy group (11.1% vs 3.4%). Long-term survival was simila