A small histopathological study of SARS and influenza autopsies compared to rejected for transplantation lungs. There is some speculation on the popular procoagulopathic nature of the panvirus, based on expression of angiotensin converting enzyme 2.There might be a collateral stimulus for lung preservation in organ retrieval.
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Use of Temporary Mechanical Circulatory Support for Management of Cardiogenic Shock Before and After the United Network for Organ Sharing Donor Heart Allocation System Changes
April 16, 2020
The UNOS donor heart allocation system was revised in 2018, giving priority to patients on inpatient mechanical circulatory support (MCS). Patients admitted with heart failure-associated cardiogenic shock were tracked for the frequency of use of mechanical circulatory support before and after implementation of this change. In non-transplant center
In Situ Expansion, Differentiation and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid
April 2, 2020
Quite refreshing well-written experimental paper leaving promises of artificial organoids.
December 19, 2019
Donor lungs undergoing EVLP were more injured, but long-term outcomes of transplant were similar between EVLP and non-EVLP lungs, including the incidence of graft dysfunction and survival.
Evaluation of the INSPIRE Trial and Its Implications for Lung Transplantation With Normothermic Portable Ex Vivo Lung Perfusion
October 30, 2019
A balanced appraisal of last year's manuscript from the Lancet Group on a relatively novel portable Organ Care System for donor lungs. The analysis of the technical complications, especially organ damage from overenthusiastic revving of the pump, is particularly sobering.
October 9, 2019
Ex vivo lung perfusion was used in 25% of transplanted lungs in the Toronto program since 2008. This resulted in an increase in the number of transplanted patients without any degradation of long-term outcomes, including survival and freedom from chronic dysfunction.
August 4, 2019
The Throacic Surgery Residents Association (TSRA) Decision Algorithms in Cardiothoracic Surgery is a 100-chapter compendium with an individual algorithm for clinical decisions spanning the entire scope of cardiothoracic surgery.
June 8, 2019
June 4, 2019
Left ventricular ejection fraction was not a predictor of outcomes after heart transplant, and was normal in all recipients at 1 year posttransplant. The reliance on generic transthoracic echocardiography for donor assessment may well be the Achilles heel of this retrospective case study.
May 21, 2019
The authors utilized a retrospective review of the UNOS database from 2007-2014 to evaluate the impact of donor sequence number (DSN) on outcomes.