In the ISCHEMIA Trial, 5179 patients with moderate or severe myocardial ischemia were randomized equally into two groups based on initial management strategy: initial invasive strategy (angiography and revascularization when feasible) and medical therapy, or initial conservative strategy (medical therapy alone and angiography if medical therapy faile
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Coronary Disease - Other
Vascular Outcomes Study of ASA Along With Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease - VOYAGER PAD
April 1, 2020
Short but promising follow-up: the intervention appears again to trade off short-term peripheral vascular complications for hitherto semi-qualified MAJOR bleed in patients undergoing revascularization for peripheral vascular disease, for an assumed considerable financial cost.
miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases
March 30, 2020
Interesting to follow up the translational potential of this rodent-model of carotid i
Percutaneous Coronary Angioplasty Versus Coronary Artery Bypass Grafting in Treatment of Unprotected Left Main Stenosis (NOBLE): A Prospective, Randomised, Open-Label, Non-Inferiority Trial
January 10, 2020
''CABG was significantly better than PCI (p=0·0066........''
November 18, 2019
An editorial related to a recent randomized controlled trial suggesting a striking benefit of anti-inflammatory secondary prevention after recent myocardial events.
October 19, 2019
Quite interesting to see that the incidence of revascularisation after multivessel PCA (the additional element on the second co-primary outcome) appears to have occured in more than 1% of the patients within three years...
September 1, 2019
Interesting viewpoint of a cardiologist on low-SYNTAX subjects.
June 27, 2019
An interesting small British-led randomized controlled trial on modern imaging of coronary atheroma.
Prophylactic Intra-Aortic Balloon Counterpulsation in High Risk Cardiac Surgery: The PINBALL Pilot Multicentre, Registry-Linked, Randomised, Controlled Feasibility Trial
June 13, 2019
An intresting pilot that was stopped due to underrecruitment. Commendable mortality in high-risk coronary artery bypass grafting.
In Global News: Prevalence of Spin in RCT Reports, Setting the Standard for Teamwork, and the Continued Public Health Challenge of Asbestos
May 24, 2019
Patient Care and General Interest Despite being the leading cause of death in the US, heart disease was the most-Googled disease in only one state: Maine.