INTEGRITTY, a group dedicated the appraisal of evidence to support optimized patient management, published a paper highlighting concerns surrounding major TAVR versus SAVR studies. While their findings do not aim to directly discredit the studies, they do raise questions about the integrity of their methodology.
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Coronary Disease - Other
2021 Coronary Revascularization Guidelines—Lessons in the Importance of Data Scrutiny and Reappraisal of Evidence
December 1, 2022
This recent JAMA Surgery editorial addresses the controversy associated with the 2021 ACC/AHA/SCAI guidelines on coronary revascularization. It underscores the importance of attention to source data and accurate characterization of evidence.
July 11, 2022
There could be some translational value for cardiovascular surgical practice from this prospective cardiovascular health study. The mechanistic link warrants further investigation and interpretation.
Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association
June 23, 2022
This scientific statement is a granular contribution to a major cardiovascular issue, illuminating nuances of the "generally recognized as safe" (GRAS) FDA designation. One would expect the relevant Thoracic Associations in North America and Europe to contribute to this debate.
April 19, 2022
Interesting manuscript on the immunology of coronary atheroma, with tanslational potential in therapies and prevention of ischaemic heart disease.
Registry for Acute Coronary Events in Nigeria (RACE-Nigeria): Clinical Characterization, Management, and Outcome
December 25, 2021
The rising burden of CAD in low- and middle-income countries like Nigeria is a result of the epidemiological transition from communicable to non- communicable diseases. The system of care for acute coronary syndrome (ACS) is evolving and constrained by a lack of prehospital emergency services, prolonged intervention times, and low patient eligibility
Minimally invasive coronary bypass surgery with bilateral internal thoracic arteries: Early outcomes and angiographic patency
November 15, 2021
Interesting in its candour mini-series of partial arterial revascularisation by left thoracotomy. The perioperative graft failure is delt in some detail.
November 9, 2021
A good-size Terumo-sponsored RCT that is set to impact on decisions to discontinue DAPT early after PCI with absorbable stent, a change that will somehow decrease the surgical risk of bleeding in the event of salvage CABG.
October 21, 2021
A large randomised double-blinded trial reporting a considerable benefit ( 0.79 HR with very small p and supporting confidence intervals) of the Boehringer SGLPT-2 inhibitor regardless of presence of formal diagnosis of diabetes.
Timing of Coronary Artery Bypass Grafting After Acute Myocardial Infarction May Not Influence Mortality and Readmissions
June 15, 2021
Fascinating confirmation of null hypotheses including bleeding complications and survival in a Pennsylvanian cohort study, despite the easily predictable previous PCI, hock, and IABP prevalence in the emergency group. The statistical model is elaborate and complex. Perhaps a randomized trial could now be justified!