Patients with proton-pump inhibitor refractory heartburn have a multitude of underlying causes. In this randomized trial of patients with refractory heartburn, only 21% had symptoms related to gastroesophageal reflux disease. Treatments included fundoplication vs omeprazole and baclofen vs omeprazole.
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October 25, 2018
Filmed at the 2018 STS Annual Meeting in Fort Lauderdale, Florida, Lisa Brown of UC Davis Medical Center in Sacramento, California, USA, moderates a discussion on the management of gastroesophageal reflux disease.
June 15, 2017
Prospective observational cohort study of 106 patients undergoing repair of giant paraesphageal hernia (GPEH) with near complete follow-up at 1 year. Outcomes measured at the first postoperative visit and at one year were radiographic recurrence, patient satisfaction and GERD-HRQL score.
February 28, 2016
The goal of this study was to determine if there is an association between PPI use and incident chronic kidney disease (CKD) in the general population.
Laparoscopic Repair of Very Large Hiatus Hernia With Sutures Versus Absorbable Mesh Versus Nonabsorbable Mesh: A Randomized Controlled Trial
January 10, 2015
This study investigated repair methods for large hiatal hernias randomized to suture only vs absorbable mesh vs nonabsorbable mesh. The design was randomized, double blind. At 12 mos the recurrence rate was 21%, with no difference among the groups. Postoperative symptoms were different among the groups, but these differences were judged to be of s
Systematic Review of the Impact of Surgical Harm on Quality of Life After General and Gastrointestinal Surgery
November 16, 2014
This article systematically reviewed the impact of surgical adverse events (SAEs) on quality of life after major GI surgery. The mean difference in QOL between pts with and without SAEs was highest for esophagectomy (0.14; scale 0 to 1), while results for antireflux surgery were mixed.