The authors have concluded from a meta-analysis of over 45,000 patients, mitral regurgitation in the presence of LV dysfunction (either ischaemic cardiomyopathy or idiopathic causes) is, not surprisingly, associated with reduced survival. Whether this is due to the underlying myopathic process or the MR per se is not clear.
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Heart Failure - Ischemic
September 9, 2017
March 29, 2017
The esteemed authors are to be commended on the detailed but readable desciption of their technique under the heading 'Indication and Surgical Technique of Extracorporeal Membrane Oxygenation and CentriMag Device' (page 753)
Does Small Size Matter With Continuous Flow Devices? : Analysis of the INTERMACS Database of Adults With BSA ≤1.5 m2
February 15, 2017
The authors reviewed the retrospective INTERMACS database to assess whether outcomes after continuous-flow (CF) LVAD implantation varied with patient BSA. A total of over 10,000 CF LVAD patients were included. Of these, 231 (2%) had a BSA < 1.5 m².
Cost-Effectiveness of Left Ventricular Assist Devices in Ambulatory Patients With Advanced Heart Failure
January 13, 2017
With the everpresent question of potentially extending LVAD therapy to ambulatory patients with advanced heart failure, the authors--using a Markov model--projected the incremental cost-efffectiveness ratio (ICER) of DT LVADs in this population as compared to conventional medical therapy.
Contemporary extracorporeal membrane oxygenation therapy in adults: Fundamental principles and systematic review of the evidence.
July 18, 2016
A handy mini-textbook on ECMO
Donor Troponin and Survival After Cardiac Transplantation. An Analysis of the United Network of Organ Sharing Registry
June 25, 2016
A large retrospective study of the UNOS database advances that elevated troponin I in selected cardiac donors is NOT associated with various adverse events. The conclusion is likely to stimulate heated discussions.
May 8, 2016
A collaborative multi-funded RCT by Chinese surgeons and European epidemiologists, this article is guaranteed to elicit thunderous responses from biomedical publishing and the pharmaceutical industry.
April 23, 2016
An editorial discussion of the impressive 10-year benefits of CABG for ischemic cardiomyopathy as found in the STICH trial.
February 2, 2016
This randomized trial (NEAT-HFpEF) of 110 subjects (59 placebos) disproves, by clinical and biological markers, the utility of nitrates for exercise tolerance. This is a subset of cardiac failure patients we are likely to encounter in general cardiothoracic surgical practice.
January 28, 2016
In this Cardiothoracic Surgical Trials Network (CTSN) trial 251 patients with ischemic mitral regurgitation were randomized to mitral-valve repair or mitral-valve replacement. The current publication reports the 2-year outcomes of the trial.