Three quarters of a century in caring for patients with congenital heart disease are summarized well in this brief viewpoint article, with the big data issue discussed.
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Heart Failure - Nonischemic
February 15, 2017
The authors reviewed the retrospective INTERMACS database to assess whether outcomes after continuous-flow (CF) LVAD implantation varied with patient BSA. A total of over 10,000 CF LVAD patients were included. Of these, 231 (2%) had a BSA < 1.5 m².
January 13, 2017
With the everpresent question of potentially extending LVAD therapy to ambulatory patients with advanced heart failure, the authors--using a Markov model--projected the incremental cost-efffectiveness ratio (ICER) of DT LVADs in this population as compared to conventional medical therapy.
November 1, 2016
An interesting case series of cardiotoxicity of modern chemotherapy attempting to elucidate mechanisms of heart failure.
July 18, 2016
A handy mini-textbook on ECMO
June 25, 2016
A large retrospective study of the UNOS database advances that elevated troponin I in selected cardiac donors is NOT associated with various adverse events. The conclusion is likely to stimulate heated discussions.
February 2, 2016
This randomized trial (NEAT-HFpEF) of 110 subjects (59 placebos) disproves, by clinical and biological markers, the utility of nitrates for exercise tolerance. This is a subset of cardiac failure patients we are likely to encounter in general cardiothoracic surgical practice.
January 9, 2016
The authors performed a randomized control study of 178 patients with heart failure and systolic dyssynchrony who were accepted for CABG, randomizing the participants into two groups: CABG alone (n=87) and CABG + concomitant epicardial CRT (n=91). CRT was activated postoperatively.
November 5, 2015
This is a very intersting case review in which the authors describe a successful heart transplant from a 37 year old donor on VV ECMO to a 62 year old female recipeint. The authors postulate that this successful outcome may expand the available donor pool for heart transplantation.
October 8, 2015
The authors evaluated ventricular function after AR or MR in young patients with regurgitation and preoperative signs of ventricular dysfunction. Results at 18 mos were compared to a normal population. Persistent LV dysfunction was present in 85% after AR+MR and was more common than after either operation alone. Preoperative end-systolic volume pr