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Heart Failure - Nonischemic

October 8, 2015
The authors evaluated ventricular function after AR or MR in young patients with regurgitation and preoperative signs of ventricular dysfunction.  Results at 18 mos were compared to a normal population.  Persistent LV dysfunction was present in 85% after AR+MR and was more common than after either operation alone.  Preoperative end-systolic volume pr
August 14, 2015
The Texas Heart Institute reports its experience with 27 patients with prior continuous flow LVADs who had undergone varying degrees of device explantation.  Although the numbers are small, the explantation methods ranged from near-complete device removal to driveline transection and removal.
January 25, 2015
This study from the University of Texas Southwestern sought to analyze the effects of mechanical unloading during prolonged LVAD support on mitochondrial mass, DNA damage response (DDR), and cardiomyocyte proliferation.  Ten matched human samples of LV myocardium were analyzed before and after mechanical circulatory support.
November 15, 2014
Selzman and colleagues provide an outstanding overview of the state of the art of bridge to recovery, describing a paradigm shift that has been occurring.  A consistent theme over the years is that recovery likelihood is enhanced in younger patients, those with non-ischemic cardiomyopathy, and those who have had HF for shorter durations.
November 10, 2014
The effects of exercise, increasing pump speed, or both on invasive hemodynamics in centrifugal flow LVAD patients were analyzed in this small study.  Findings included:
May 21, 2014
The authors present results of surgery in 12 pts for hypertrophic cardiomyopathy extending to the papillary muscles.  Repair was performed through a detached anterior mitral leaflet, which was subsequently repaired.  The intraventricular end-diastolic gradient was decreased by 80% postop, and mitral regurgitation that was present preop was eliminated
May 7, 2014
Results of a 50 year experience with surgery for cortriatriatum sinister were summarized.  A mix of infants and adults underwent treatment, consisting of membrane excision on CPB.  10 year survival was 83%, and all patients were in NYHA class I or II at follow-up. 

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