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Intensive Care - Systemic Diseases

March 27, 2018
A succinct balanced editorial advancing, amongst other things, the position for initial nonintervention for submassive pulmonary embolism.
March 8, 2018
A handy view from the pediatric standpoint on an expanding indication for sequential pulmonary transplanation.
February 23, 2016
This consensus effort provides a new definition for septic shock, which affects a subset of patients with sepsis.   The definition requires the presence of circulatory disturbances (BP unresponsive to fluids and requiring pressors), cellular and metabolic abnormalities (serum lactate level >2 mmol/L).  The presence of these criteria is associated
November 10, 2014
The authors explored a sample of Medicare patients who survived sepsis during hospitalization to assess the impact of afib developing during sepsis on long-term outcomes.  Of nearly 139,000 sepsis survivors, 7% had new onset afib during sepsis.  Of those pts, 55% were found to have afib after hospitlization.  New onset afib during sepsis was associat
September 29, 2014
This randomized double-blind multicenter study involving 667 pts evaluated the utility of IV fenoldopam in reducing the rate of renal replacement therapy for patients undergoing cardiac surgery who exhibit postoperative acute kidney injury.  Fenoldopam did not importantly reduce the need for renal replacement therapy or 30 day mortality.  Its use was
August 11, 2014
In an effort to identify clinical findings associated with deterioration and mortality after PE, the authors prospectively monitored 298 pts admitted through the ED with documented PE.  34% of pts experienced clinical deterioration, which was associated with hypotension, hypoxia, residual DVT, CAD, and right heart strain on echocardiogram.  In contra
June 16, 2014
Using data from the Australian Cardiac Surgical Database, the authors provide further information regarding acute kidney damage after cardiac surgery. This study has added to the evidence that preoperative impairment, IABP use, red cell transfusion and infective endocarditis are predictive factors.
June 16, 2014
The rate of cerebral embolism in patients with acute infective endocarditis (AIE) was about one quarter on CT scanning, with about one third having silent emboli. This had an adverse impact on survival. Haemorrhagic transformation was low. The authors indicate CT scanning should be routine for all patients with AIE.

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