In this retrospective review of the effects of radiation dose to the heart on long-term outcomes, 748 patients with regionally advanced non–small cell lung cancer were studied. An increasing cardiac radiotherapy dose was associated with an increased risk of MACE and all-cause mortality.
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Lung Cancer - Radiation Therapy
Measuring the Integration of Stereotactic Ablative Radiotherapy Plus Surgery for Early-Stage Non–Small Cell Lung Cancer
March 4, 2019
The complete pathologic response rate in this study is revealed to be low, lower than expected after stereotactic ablative radiotherapy (SABR) for early stage non-small cell lung cancer: only 60%. The authors suggest a combined approach (SABR plus surgery), adopted in this experimental phase 2 trial, as a possible management scheme.
A Systematic Review and Meta-Analysis of Stereotactic Body Radiation Therapy Versus Surgery for Patients With Non–Small Cell Lung Cancer
January 9, 2019
Cao and colleagues compared outcomes with stereotactic body radiation therapy (SBRT) to surgery for patients with non–small cell lung cancer using a meta-analysis of 23 studies.
December 6, 2018
Kevin Franks of the Leeds Cancer Centre in the UK discusses recent advances in radiotherapy technology for the treatment of lung cancer.
Aggressive Radiotherapy, Surgery Doubles Overall Survival in Non-Small Cell Lung Cancer With Limited Mets
October 23, 2018
Forty-nine patients with limited metastatic non-small cell lung cancer (three or fewer metastatic sites) who did not progress on initial systemic therapy were randomized to surgery or RT vs standard maintenance therapy. Overall survival for the intervention group was 41.2 mos vs 17.0 mos in those getting maintenance therapy (p=0.017).
Adding Radiotherapy to Adjuvant Chemotherapy Does Not Improve Survival of Patients With N2 Lung Cancer
October 11, 2018
This analysis of the National Cancer Database included over 2000 eligible patients resected with N2 disease who did not receive induction therapy. The addition of radiotherapy to postoperative chemotherapy did not affect survival in either the unmatched or the matched groups.
Concurrent Versus Sequential Chemoradiation Therapy in Completely Resected Pathologic N2 Non-Small Cell Lung Cancer: Propensity-Matched Analysis of the National Cancer Data Base
April 13, 2018
The authors found that adjuvent chemoradiotherapy after resection of N2 NSCLC was more effective if given sequentially than concomitantly.
In Global News: Smallest Heart Valve for Infants, a Modified TAVR Valve for TMVR, and Thoracic Outlet Surgery Fashion
March 9, 2018
Patient Care Carter Capps, a pitcher for professional baseball team the San Diego Padres, has made himself a necklace out of the rib surgeons removed during his thoracic outlet surgery.
March 8, 2018
Eric Lim of the Royal Brompton Hospital in London, UK, discusses the rise of competing technology in radiotherapy and its effect on general thoracic surgery.
The Great Debate Flashes: Surgery Versus Stereotactic Body Radiotherapy as the Primary Treatment of Early-Stage Lung Cancer
February 26, 2018
Weder and colleagues present a debate addressing surgery versus stereotactic body radiotherapy as the primary treatment of early-stage lung cancer. Arguments relating to outcome and the impact on further therapy are given by both surgeons and radiation oncologists.