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Off-pump Bypass

April 7, 2015
The authors prospectively performed coronary angiograms in their patients undergoing isolated CABG who demonstrated a rising cardiac troponin I profile in the first 12 hours following heart surgery - despite being asymptomatic.  Among a total of 1693 patients from 2005-2011, 29 (1.7%) of patients had a rising CTnI.
February 28, 2015
Comparing 714 on pump and 714 off pump CABG patients, the investigators investigated the incidence of Acute Kidney Injury (AKI) and whether cardiopulmonary bypass time and or duration were independent contributors to AKI.  The investigators concluded that there are no differences in the incidence of AKI during  CABG surgery employing CPB.
January 18, 2015
Anemic off-pump CABG (n=361) versus on-pump CABG (n=578) patients were compared.  In anemic patients, off-pump CABG was associated with lower early morbitidy and mortality. 1 to 6 month follow-up mortality, however, was higher in the off-pump CABG cohort.
November 7, 2014
A multicenter, randomized, controlled trail including 900 patients divided patients into those undergoing on-pump versus off-pump CABG.  Identical heparinization and heparin reversal protocols were followed.  At angiography at 6 months following CABG, graft patency was inferior after off-pump as compared to on-pump  revascularization.
October 11, 2014
In a cohort of 11,922 diabetic patients undergoing CABG, the authors compare single versus bilateral internal thoracic artery grafting (BITA), complete versus incomplete revascularization, and on versus off-pump CABG.  The authors conclude that BITA with complete revascularization maximizes long-term survival.
September 15, 2014
This descriptive study presents the peri-operative and 1-year results of on-pump and off-pump surgery performed in patients enrolled in the Arterial Revascularization Trial (ART). Out of the 3102 patients randomised in the ART trial to undergo either single or bilateral mammary artery grafting, 41% had their surgery performed off-pump.
August 18, 2014
Bakaeen and colleagues have retrospectively reviewed the use of off-pump surgery among 2137841 primary isolated CABG operations in the Society of Thoracic Surgeons Database. They showed that off-pump procedures peaked in 2002 with 23% of CABG operations, after which it declined to 17% in 2012.
June 5, 2014
This large-scale study evaluated kidney function postoperatively and at 1 year after either on-pump or off-pump isolated first time CABG.  Nearly 3000 pts were enrolled over a 2 year period.  Outcomes were a >50% increase in creatinine within 30 days of operation (AKI) and >20% loss of GFR at 1 year.  Off-pump bypass was associated with a lower
April 24, 2014
Long-term survival following coronary artery bypass grafting: off-pump versus on-pump strategies JACC - Journal of the American College of Cardiology, 04/18/2014  Evidence Based Medicine  Clinical Article  

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