Clinical trials evaluating transcatheter mitral valve interventions for severe mitral regurgitation (MR) are complex.
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Transcatheter Mitral Intervention
Clinical Trial Design Principles and Endpoint Definitions for Transcatheter Mitral Valve Repair and Replacement: Part 1: Clinical Trial Design Principles: A Consensus Document From the Mitral Valve Academic Research Consortium
July 27, 2015
May 27, 2015
In this manuscript the authors describe their finding after a systematic review and meta-analysis to explore the safety and efficacy of the Mitraclip procedure for patients with functional mitral regurgitation (FMR). Overall, 875 patients were included. Every patient underwent a follow-up of at least 6 months.
Comparison of Outcomes of Percutaneous MitraClip Versus Surgical Repair or Replacement for Degenerative Mitral Regurgitation in Octogenarians.
December 28, 2014
This is a retrospective study comparing outcomes in 25 octogenarian patients undergoing percutaneous mitral valve intervention with the Mitraclip device and 35 octogenarian patients undergoing surgical mitral valve repair or replacement for isolated mitral regurgitation.
May 25, 2014
Interesting images of one of the very few reports on transeptal mitral valve implantation, in this case with a SAPIEN XT valve. The valve was implanted in a 72-year old female patient with previous aortic valve replacement and tricuspid valve annuloplasty. She had symptomatic mitral stenosis with severe calcification of the mitral annulus.
First Bioprosthesis Thrombosis After Transcatheter Mitral Valve-in-Valve Implantation: Diagnosis and Treatment
May 8, 2014
An interesting case that raises the question of the need for anticoagulation in patients treated with a transcatheter valve in valve in mitral position