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Hiroyuki Tsukui

Hiroyuki Tsukui, M.D., Ph.D.

Excela Health Westmoreland Hospital
44 South Washington Avenue
Medical Commons Three
Greensburg, PA  15601
United States
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Surgeon - Cardiothoracic


Niigata University (M.D. 1995)
Tokyo Women's Medical University (Ph.D. 2006)
Tokyo Women's Medical University Cardiovascular Surgery Residency (1995-2002)
Research Fellow McGowan Institute of Regenerative Medicine, University of Pittsburgh (2003-2004)
Clinical Fellow, Artificial Heart and Thoracic Transplantation, UPMC (2004-2006)
Clinical Fellow, Advanced Adult Cardiac Surgery, University of Pittsburgh Medical Center (2006-2008)
Assistant Professor, Tokyo Women's Medical University Cardiovascular Surgery (2009-2016)
CEO and Chief of Cardiovascular Surgery, Hokkaido Cardiovascular Hospital (2016-2019)
Temporary Associate Professor, Department of Cardiovascular Surgery, Tokyo Women’s Medical University (2016-)
Clinical Professor, Department of Cardiovascular Surgery, Sapporo Medical University (2018-2019)
Clinical Teaching Professor, Department of Cardiovascular Surgery, Asahikawa Medical University (2019)
Associate Director, Excela Health Westmoreland Hospital (2019-2022)
Director, Excela Health Westmoreland Hospital (2022-Current)

Other Interests

Complex Mitral Valve Repair
Minimally Invasive Mitral Valve Repair
Robotic Cardiac Surgery
Off-pump Coronary Artery Bypass Grafting
Hemodialysis in Cardiac Surgery


  1. Nishi H, Yokoyama H, Yaku H, Doi K, Nishimura Y, Abe K, Tsukui H, Tabata M, Okamoto K, Park YK, Matsuda H. Efficacy of simulation training for beating heart coronary anastomosis using BEAT + YOUCAN simulator Asian Cardiovasc Thorac Ann. 2021 Nov 10:2184923211060214. doi: 10.1177/02184923211060214.
  2. Kunioka S, Fujita K, Iwasa S, Kamiya H, Yamazaki K, Tsukui H. Non-pledget commissural suture technique to avoid atrioventricular block. Gen Thorac Cardiovasc Surg 2021; Feb 19.
  3. Kunioka S, Fujita K, Iwasa S, Murakami H, Kamiya H, Yamazaki K, Tsukui H. A rare form of cardiac myxoma: interatrial septum tumor. J Surg Case Rep. 2020; 9: 1-4.
  4. Tsukui H, Iwasa S, Yamazaki K. Prosthetic Valve Removal Technique Using Ultrasonic Scalpel. Ann Thorac Surg. 2019; 108: e273-4.
  5. Konishi T, Yamamoto T, Hayakawa M, Iwasa S, Tsukui H, Tanaka S. Multimodal imaging of right coronary artery to left ventricle fistula complicated by large coronary aneurysm. Cardiol J. 2019; 26: 93-94.
  6. Katsube T, Saito S, Tsukui H, Yamazaki K, Niinami H. Modified David-Komeda Repair for Ventricular Septal Perforation Complicated with Severe Postoperative Acute Respiratory Distress Syndrome; Report of a Case. Kyobu Geka. 2018; 71: 953-956.
  7. Tsukui H, Iwasa S, Yamazaki K. Management of Cardiac Surgery in Hemodialysis Patients. J Jpn Soc Blood Purif Crit Care 2016; 7: 141-146
  8. Tsukui H, Shinke M, Park YK, Yamazaki K. Longer coronary anastomosis provides lower energy loss in coronary artery bypass grafting. Heart Vessels 2017; 32: 83-89.
  9. Saito S, Tsukui H, Iwasa S, Umehara N, Tomioka H, Aomi S, Yamazaki K. Bileaflet mechanical valve replacement: an assessment of outcomes with 30 years of follow-up. Interact Cardiovasc Thorac Surg 2016; 23: 599-607.
  10. Tsukui H, Iwasa S, Yamazaki K. Left Atrial Dissection. Gen Thorac Cardiovasc Surg 2015; 63: 434-45.
  11. Tsukui H, Iwasa S, Yamazaki K. Left Atrial Dissection Related to Retrograde Cardioplegia Cannula Insertion. Heart Vessels 2016; 31: 819-821
  12. Tsukui H. Transplantation and the Most Advanced Medical Treatment Transplantation (7) Heart Transplantation. J Tokyo Women’s Medical University 2014; 84: 133-9
  13. Tsukui H. Study in abroad. University of Pittsburgh Medical Center. Kyobu Geka 2014; 67: 1096-7.
  14. Tsukui H, Aomi S, Yamazaki K. Reply to the editor. J Thorac Cardiovasc Surg 2014; 148: 361-2.
  15. Maeda T, Tsukui H, Umehara N, Iwasa S, Sugiura T, Hayakawa M, Kawano Y, Yamazaki K: Warfarin effects diminishment by the clostridium butyricum preparation after cardiac surgery; report of a case. Kyobu Geka 2014; 67: 505-507
  16. Saito S, Yamazaki K, Nishinaka T, Ichihara Y, Ono M, Kyo S, Nishimura T, Nakatani T, Toda K, Sawa Y, Tominaga R, Tanoue T, Saiki Y, Matsui Y, Takemura T,  Niinami H, Matsumiya G; J-MACS Research Group. Post-approval study of a highly pulsed, low-shear-rate, continuous-flow, left ventricular assist device, EVAHEART: a Japanese multicenter study using J-MACS. J Heart Lung Transplant. 2014; 33: 599-608.
  17. Tsukui H, Aomi S, Yamazaki K: Surgical Strategy for Kommerell’s Diverticulum: Total Arch Replacement. J Thorac Cardiovasc Surg 2014; 148: 1423-7
  18. Tsukui H, Yamazaki K: Contemporary Strategy for Aortic Valve Stenosis in Octogenarians. Surgery Today 2013; 44: 992-1003.
  19. Tsukui H, Umehara N, Saito H, Saito S, Yamazaki K: Early Outcome of Folding Mitral Valve Repair Technique Without Resection for Mitral Valve Prolapse in 60 Patients. J Thorac Cardiovasc Surg; 2013; 145: 104-8
  20. Tsukui H. Reply to the editor. J Thorac Cardiovasc Surg. 2013; 145: 1687.
  21. Tsukui H, Yamazaki K: Imaging diagnosis: Q & A. Right ventricular perforation by an ICD lead. Kyobu Geka 2012; 65: 1076-1079
  22. Tsukui H, Umehara N, Yamazaki K: Left ventricular aneurysm repair without ventriculotomy. Heart Vessels 2013; 28: 401-403
  23. Tsukui H: Manufacturing sales approval for implantable ventricular assist device. Medical Technology 2011; 39: 418-419
  24. Yumino D, Tsukui H, Minami Y, Kikuchi N, Shiga T, Yamazaki K, Hagiwara N: Medical Treatment for severe heart failure. Kokyuu to Junkan 2011; 59: S2-5
  25. Tsukui H: Implantable ventricular assist device. Jinkou Zouki 2010; 39: 150-153
  26. Tsukui H: Off-pump CABG training system. Jinkou Zouki 2010; 39: 218-221
  27. Tsukui H: Surgical Treatment for End-stage Heart Failure in the Future in Japan J Niigata Med Assn 2009; 715: 2-7
  28. Tsukui H, Yamazaki K: Brain Death Organ Transplant and Ventricular Assist Device – Relationship of Mutual Complement - Jpn J Transplant 2009; 44: S214-6
  29. Tsukui H: Introduction of Physician Extenders to Cardiovascular Surgery in Japan. Nippon Geka Gakkai Zasshi. 2009; 110:110-2.
  30. Tsukui H, Abla A, Teuteberg JJ, McNamara DM, Mathier MA, Kormos RL: Cerebrovascular Accidents in Patients with a Ventricular Assist Device. J Thorac Cardiovasc Surg 2007; 134: 114-23
  31. Snyder TA, Litwak KN, Tsukui H, Akimoto T, Kihara S, Yamazaki K, Wagner WR: Leukocyte-platelet aggregates and monocyte tissue factor expression in bovines implanted with ventricular assist devices. Artif Organs. 2007; 31: 126-31.
  32. Snyder TA, Tsukui H, Kihara S, Akimoto T, Litwak KN, Kameneva MV, Yamazaki K, Wagner WR: Preclinical biocompatibility assessment of the EVAHEART ventricular assist device: Coating comparison and platelet activation. J Biomed Mater Res A. 2007; 81:85-92.
  33. Borovetz HS, Badylak S, Boston JR, Johnson C, Kormos R, Kameneva MV, Simaan M, Snyder TA, Tsukui H, Wagner WR, Woolley J, Antaki J, Diao C, Vandenberghe S, Keller B, Morell V, Wearden P, Webber S, Gardiner J, Li CM, Paden D, Paden B, Snyder S, Wu J, Bearnson G, Hawkins JA, Jacobs G, Kirk J, Khanwilkar P, Kouretas PC, Long J, Shaddy RE: Towards the development of a pediatric ventricular assist device. Cell Transplant. 2006; 15 Suppl 1: S69-74.
  34. Wearden PD, Morell VO, Keller BB, Webber SA, Borovetz HS, Badylak SF, Boston JR, Kormos RL, Kameneva MV, Simaan M, Snyder TA, Tsukui H, Wagner WR, Antaki JF, Diao C, Vandenberghe S, Gardiner J, Li CM, Noh D, Paden D, Paden B, Wu J, Bearnson GB, Jacobs G, Kirk J, Khanwilkar P, Long JW, Miles S, Hawkins JA, Kouretas PC, Shaddy RE: The PediaFlow pediatric ventricular assist device.
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006; 92-8.
  35. Tsukui H, Teuteberg JJ, Murali S, McNamara DM, Buchanan JR, Winowich S, Stanford E, Mathier MA, Cadaret LM, Kormos RL: Biventricular Assist Device Utilization for Patients with Morbid Congestive Heart Failure: A Justifiable Strategy. Circulation 2005; 112[suppl I]: I-65-I-72.
  36. Ogawa M, Tsukui H, Ishii H, Yokoyama S, Koh E: Clinical evaluation of hydrocolloidal dressing in 147 patients undergoing cardiovascular surgery. Kyobu Geka. 2005; 58: 555-8.
  37. Litwak KN, Koenig SC, Tsukui H, Kihara S, Wu Z, Pantalos GM: Effects of left ventricular assist device support and outflow graft location upon aortic blood flow. ASAIO J 2004; 50: 432-37
  38. Tsukui H, Koh E, Yokoyama S, Ogawa M: Which patients can be weaned from inotropic support within 24 hours after cardiac surgery. Heart Vessels 2004;19: 239-42
  39. Tsukui H, Koh E, Yokoyama S, Ogawa M, Kato G, Saitoh H:Bilateral coronary ostial stenoses with aortic regurgitation in a patient with syphilitic aortitis. Kyobu Geka 2003; 56: 158-60
  40. Ogawa M, Tsukui H, Yokoyama S, Koh E, Shiraishi Y, Hirasaki T, Ishibashi K: Combined operation for left ventricular aneurysm and ventricular septal perforation with normal coronary arteries; report of a case. Kyobu Geka 2003; 56: 239-42.
  41. Tsukui H, Hoshino S, Saito N, Nishiya Y, Usuda K: Successful surgical treatment of ventricular tachycardia that induced left ventricular aneurysm in 12-year-old boy. Minerva Pediatr 2002; 54: 53-56.
  42. Tsukui H, Aomi S, Tomioka H, Nonoyama H, Koyanagi H, Nagasawa C, Nomura M: Arch-first Technique Versus Conventional Method for Aortic Arch Operation Using Branched Graft. Asian Cardiovasc Thorac Ann 2002; 10: 318-21.
  43. Tsukui H, Aomi S, Endo M, Koyanagi H: Acute aortic dissection in a patient with idiopathic dilated cardiomyopathy. Jpn J Thorac Cardiovasc Surg 2002; 50: 309-310
  44. Tsukui H, Koh E, Yokoyama S, Ogawa M: Surgical repair of left ventricular free wall rupture using layered fibrin glue sheet and fibrin glue; report of a case Kyobu Geka 2002; 55: 887-890.
  45. Tsukui H, Aomi S, Nishida H, Endo M, Koyanagi H: Ostial stenosis of coronary arteries following complete replacement of aortic root using GRF glue. Ann Thorac Surg 2001; 72: 1733-35.
  46. Tsukui H, Hoshino S, Saito N, Nishiya Y: Giant extracardiac unruptured aneurysm of sinus of Valsalva: a case report. Heart Vessels 2001; 15: 289-90.
  47. Tsukui H, Tomizawa Y, Saito N, Hoshino S, Nishiya Y: Effect of oral pretreatment with taurine (2-aminoethanesulfonic acid) in acute phase after cardiac surgery. ICU and CCU 2001; 25: 947-953.
  48. Tsukui H, Endo M, Hirasawa Y, Chikazawa G, Kurihara T, Tomizawa Y, Kawai A, Aomi S, Nishida H, Koyanagi H: Postoperative rupture of abdominal aortic aneurysm in patients with ischemic heart disease and other organ disease. Kyobu Geka 2001; 54: 370-373.
  49. Tsukui H, Hoshino S, Saito N, Nishiya Y: Experiences of minimally invasive great saphenous vein graft harvest using with Endopath. Kyobu Geka 2001; 54: 128-131.
  50. Isomatsu Y, Tsukui H, Hoshino S, Nishiya Y: Predicting blood transfusion factors in coronary artery bypass surgery. Jpn J Thorac Cardiovasc Surg 2001; 49: 438-42.
  51. Miyata K, Matsumura H, Uehara M, Tsukui H, Ogawa M, Fujita M: The effect of thrombolysis and stent placement for an extremely old woman’s left iliac artery occlusion. Jpn J Vasc Surg 2001; 10: 619-622.
  52. Nishida H, Tsukui H, Shimabukuro T, Nakajima M, Uchikawa S, Ozawa H, Chikazawa G, Maeda T, Yamazaki K, Tomizawa Y, Kawai A, Aomi S, Endo M, Koyanagi H, Nikaido H, Tanaka M, Endo N: Effectiveness of IABP during on pump CABG in patients with significant stenosis in cervical and cerebral arteries who are not amenable to off pump CABG. Cardioangiology 2001; 49: 280-281.
  53. Isomatsu Y, Tsukui H, Hoshino S, Nishiya Y: Cardiac surgery for Takayasu’s disease.  Jpn J Cardiovasc Surg 2001; 30: 15-18.
  54. Tsukui H, Imai Y, Takanashi Y, Terada M, Hiramatsu T.: Anatomic biventricular correction by taking down bicaval Glenn shunt. Ann Thorac Surg 2000; 69: 1268-70.
  55. Isomatsu Y, Tsukui H, Hara M, Hoshino S, Nishiya Y: A case of acute pulmonary embolism fourteen days after hysterectomy. Kyobu Geka 2000; 53: 687-90.
  56. Isomatsu Y, Hoshino S, Tsukui H, Hara M, Nishiya Y, Ishikawa T: Regression of left main coronary ostium stenosis after surgical revascularization and steroid therapy. Jpn J Thorac Cardiovasc Surg 2000; 48: 594-6.
  57. Usuda K, Kobayashi D, Takemori H, Ishikawa T, Hoshino S, Saito N, Tsukui H, Nihsiya Y, Kubo M: A pediatric case of congenital left ventricular aneurysm associated with life threatening ventricular tachycardia. Shinzou 2000; 32, 58-93
  58. Tsukui H, Saito N, Isomatsu Y, Hoshino S, Nishiya Y: Effective hemostasis by using disposable plastic injector after intraaortic balloon pumping. ICU and CCU 1999; 23: 629-631.
  59. Tsukui H, Aomi S, Toyama S, Kunii Y, Nishinaka T, Maeda T, Koyanagi H: Two cases of infected aortic abdominal aneurysm with spondylodiskitis. Jpn J Cardiovasc Surg 1999; 28: 121-124.
  60. Isomatsu Y, Nishiya Y, Hoshino S, Hara M, Tsukui H: Left atrial myxoma associated with acute myocardial infarction. Jpn J Thorac Cardiovasc Surg 1999; 47: 452-4.
  61. Tsukui H, Ohara K, Akimoto T, Mukaida M, Abe K: Case report of surgical repair of left ventricular free wall rupture using GRF glue and pericardial patch. J Jpn Assn Thorac Surg 1998; 46: 898-901.
  62. Tsukui H, Ohara K, Akimoto T, Mukaida M, Abe K: Three cases of right-sided active endocarditis with multiple pulmonary infarction. J Jpn Assn Thorac Surg 1998; 46: 75-80.
  63. Tsukui H, Aomi S, Kurihara T, Otsuka G, Kitamura M, Koyanagi H: Sternotomy approach in a case of giant ascending aortic aneurysm and annuloaortic ectasia previously operated for pure pulmonary stenosis. Jpn J Cardiovasc Surg1998; 27: 67-70.
  64. Tsukui H, Ohara K, Akimoto T, Mukaida M, Abe K: The waffle procedure (multiple incision of epicardium) with pericardiectomy for constrictive pericarditis. J Jpn Assn Thorac Surg 1997; 45: 1981-1985.
  65. Tsukui H, Kitamura M, Hachida M, Kunii Y, Uesugi H, Saito S, Ishitoya H, Hirata K, Koyanagi H: Aortic valve replacement with the Toronto Stentless Porcine Valve in a patient with clipping for cerebral arterial aneurysm. Kyobu Geka 1997; 50: 565-568.
  66. Ohtsuka G, Aomi S, Koyanagi H, Tsukui H, Tomizawa Y, Hashimoto A, Sakomura Y: Heart valve operation in acromegaly. Ann Thorac Surg 1997; 64: 390-393.
  67. Otsuka G, Kitamura M, Ishitoya H, Tsukui H, Hachida M, Aomi S, Hashimoto A, Koyanagi H: Simultaneous tricuspid valve operation in patients undergoing aortic and mitral double valve replacement. Kyobu Geka 1997; 50: 351-355.
  68. Akimoto T, Ohara K, Tei I, Mukaida M, Tsukui H: Cardiovascular surgery in nine patients with chronic renal failure –Efficiency of acute peritoneal dialysis- J Jpn Coll Surg 1996; 21: 814-818