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Association of Blood Transfusion From Female Donors With and Without a History of Pregnancy With Mortality Among Male and Female Transfusion Recipients

Wednesday, October 18, 2017

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Camila Caram-Deelder, Aukje L. Kreuger, Dorothea Evers, Karen M. K. de Vooght, Daan van de Kerkhof, Otto Visser,Nathalie C. V. Péquériaux, Francisca Hudig, Jaap Jan Zwaginga, Johanna G. van der Bom, Rutger A. Middelburg

The authors report the non-intuitive finding that blood from female donors who had ever been pregnant was associated with increased mortality among male recipients (HR 1.13).   If validated by other studies, might this substantially complicate matching donated blood with appropriate recipients?  Clearly the underlying mechanism will be interesting to sort out.

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