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Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 1988–2012: A Single-institution, High-volume Experience in China

Wednesday, December 23, 2015

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Liu, Kai; Yang, Kun; Zhang, Weihan; Chen, Xiaolong; Chen, Xinzu; Zhang, Bo; Chen, Zhixin; Chen, Jiaping; Zhao, Yongfan; Zhou, Zongguang; Chen, Longqi; Hu, Jiankun

This longitudinal review of single institution experience with GEJ adenocarcinomas identified time-related trends.  The proportion of GEJ tumors compared to all esophageal cancers increased from 22% to 36%.  GERD increased from 7% to 11%.  An increased in GERD was associated with an increased in the prevalance of Seiwert I tumors.  There was  a significant increase in the use of total gastrectomy to treat these cancers (20% vs 42%).

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