This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Effectiveness of Biatrial Epicardial Application of Amiodarone Releasing Adhesive Hydrogel to Prevent Postoperative AF

Sunday, June 1, 2014

Submitted by


Source Name: The Journal of Thoracic and Cardiovascular Surgery


Wang, William Feng, Xiao Dong Wang, Xue Ning Yuan, Xin Hiu

This study assessed whether the application of a poly based hydrogel containing amioderone applied to the epicardium at the time of surgery reduced the incidence of post-operative atrial fibrillation. The study randomised 100 patients undergoing cardiac surgery to either receive the amioderone spray at the time of surgery or no intervention. Patients in who received epicardial amioderone had a significantly reduced incidence of post-operative AF (4/50, 8%) compared to the control group (13/50, 26%) up to 14 days post-surgery. Plasma amioderone levels remained below the detection limit for the duration of the study.    

Add comment

Log in or register to post comments