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Evaluation of Esophageal Anastomotic Integrity With Serial Pleural Amylase Levels
Miller and colleagues retrospectively compared anastomotic integrity with pleural amylase levels (PAL), measured daily from postoperative day 3-10 after an Ivor Lewis esophagectomy. Three of 45 patients had an anastomotic leak, each of which coincided with a large increase in their PAL. The authors conclude that measuring PALs is an accurate, safe, and inexpensive way to detect esophageal anastomotic leaks.