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Idarucizumab for Dabigatran Reversal — Full Cohort Analysis
In this study, the Dabigatran reversal-drug Idarucizumab was tested. 503 patients were enrolled, of whom 202 had to undergo an urgent procedure. Of the patients requiring an urgent procedure, the median time of initiation of the procedure was 1.6 hours, and at that time periprocedural hemostasis was assessed as normal in 93.4% of the patients. At 90 days, thrombotic events had occurred in 7.4% of the patients requiring an urgent procedure and the mortality rate was 18.9%. The results of this study show that Idarucizumab is a rapid and effective reversal drug for the effects of Dabigatran in case of the need for urgent surgery. As Dabigatran is increasingly being used in patients with atrial fibrillation, the availability of Idarucizumab is important.