ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Impact of Hematologic Malignancies on Outcome of Cardiac Surgery

Wednesday, August 19, 2020

Submitted by

Saurabh Gupta

Source

Source Name: Annals of Thoracic Surgery

Source URL: https://www.annalsthoracicsurgery.org/article/S0003-4975(20)31326-6/pdf

Author(s)

Anita Nguyen, MBBS MS; Hartzell V. Schaff, MD; Arman Arghami, MD; Gabor Bagameri, MD; M. Sertac Cicek, MD; Juan A. Crestanello, MD; Richard C. Daly, MD; Kevin L. Greason, MD; Alberto Pochettino, MD; Phillip G. Rowse, MD; John M. Stulak, MD; Brian D. Lahr, MS; Joseph A. Dearani, MD

The authors created 612 matched pairs of patients with a history of hematologic malignancy and controls. They compared operative details, early postoperative complications, and late survival.

Patients with prior diagnosis of malignancy had lower hemoglobin levels and were at greater risk of receiving postoperative blood transfusions (47.4% vs. 35.6%, P<0.0001).
Reoperations for postoperative bleeding (4.7% vs. 3.3%, P=0.253) and stroke (1.3% vs. 1.3%, P>0.999) were similar. Thirty-day mortality in patients with hematologic malignancy was 3.3%, and 1.5% in matched controls (P=0.061).
Overall survival among patients with cancer was reduced (P<.0001).

The authors concluded that while late survival is reduced in patients with hematologic malignancies, early outcomes are generally similar to matched controls. As such, these patients should be offered surgery.