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Implementation of Minimally Invasive Esophagectomy From a Randomized Controlled Trial Setting to National Practice

Saturday, June 27, 2020

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Source Name: Journal of Clinical Oncology


Sheraz R. Markar, Melody Ni, Suzanne S. Gisbertz, Leonie van der Werf, Jennifer Straatman, Donald van der Peet, Miguel A. Cuesta, George B. Hanna, and Mark I. van Berge Henegouwen, on behalf of the Dutch Upper GI Cancer Audit and TIME Study Group

The previous randomized study of minimally invasive esophagectomy vs open esophagectomy (TIME trial) conducted in the Netherlands demonstrated reduced pulmonary complications and LOS with MIE.  Compared to the benefits of MIE in those selected high volume centers, national use of MIE was associated with increased overall complications, increased pulmonary complications, and increased reoperation rates. 

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