This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Long-Term Outcomes of Chordal Replacement With Expanded Polytetrafluoroethylene Sutures to Repair Mitral Leaflet Prolapse

Wednesday, August 12, 2020

Submitted by


Source Name: The Journal of Thoracic and Cardiovascular Surgery


Tirone E. David, MD; Carolyn M. David, BN; Myriam Lafreniere-Roula, PhD; Cedric Manlhiot, PhD

David et al. examined the durability of mitral repair using using chordal replacement with expanded polytetrafluoroethylene sutures to correct leaflet prolapse.They evaluated 186 patients who underwent isolated chordal replacement, and 560 patients who underwent both leaflet resection and choral replacement.

The authors demonstrated that re-do cardiac surgery and isolated anterior leaflet prolapse resulted in an increased hazard of mitral valve reoperation. The probability of recurrent moderate or severe mitral regurgitation using repeated measures regression models was 14.1% at 20 years. Variables associated with recurrent MR in multivariable regression analysis were left ventricular ejection <40% and preoperative complete heart block. 
David et al. note that chordal replacement with expanded polytetrafluoroethylene sutures provides stable mitral valve function in most patients during the 20 years of follow-up.


Add comment

Log in or register to post comments