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Magnesium Status and Magnesium Therapy in Cardiac Surgery: A Systematic Review and Meta-analysis Focusing on Arrhythmia Prevention

Thursday, July 6, 2017

Submitted by

Arie Blitz

Source

Source Name: Journal of Critical Care

Source URL: http://www.jccjournal.org/article/S0883-9441(16)31047-4/fulltext?rss=yes

Author(s)

Jessica L. Fairley, MBBS, Hons, Ling Zhang, MD, Neil J. Glassford, MBChB, MRCP, Rinaldo Bellomo, MBBS, MD, FRACP, FCICM

The authors conducted a meta-analysis of 35 RCTs analyzing the use of IV Mg for the prevention or treatment of arrhythmias following cardiac surgery. The studies included had significant methodological heterogeneity.

Findings: Mg use was associated with a reduction in Afib as well as ventricular arrhythmias postop, with a RR of 0.69 (p=0.002) and 0.46 (p=.004), respectively.