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Methylene blue for postcardiopulmonary bypass vasoplegic syndrome: A cohort study

Tuesday, May 23, 2017

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Source Name: Annals of Cardiac Anesthesia


Michael Mazzeffi1, Benjamin Hammer2, Edward Chen3, Mark Caridi-Scheible4, James Ramsay5, Christopher Paciullo6

The authors conducted a retrospective cohort study of 88 patients that received methylene blue (MB) for refractory vasoplegia following cardiopulmonary bypass.  Administration of MB was associated with an 8 mmHg increase in mean arterial pressure, with the peak response occurring at 2 hours after completion of dose.  

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