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Nadir Hematocrit on Bypass and Rates of Acute Kidney Injury: Does Sex Matter?

Monday, November 16, 2015

Submitted by

Mark Ferguson

Source

Source Name: Annals of Thoracic Surgery

Source URL: http://www.annalsthoracicsurgery.org/article/S0003-4975%2815%2900919-4/abstract

Author(s)

Michelle C. Ellis, Theron A. Paugh, Timothy A. Dickinson, John Fuller, Jeffrey Chores, Gaetano Paone, Michael Heung, Karsten Fliegner, Andrew L. Pruitt, Himanshu J. Patel, Min Zhang, Richard L. Prager, Donald S. Likosky, for the PERForm Registry and the Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative

Data from a large multicenter registry were evaluated to determine whether there is a sex difference in susceptibility to acute kidney injury after CBP related to nadir hematocrit levels. Based on a 21% hematocrit threshold, 9.5% of men and 31.9% of women were affected. Rates of AKI were similar between the sexes. There was a strong interaction betwen sex and nadir Hct level; men were significantly more susceptible to AKI related to nadir Hct.