ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

PCI of Native Coronary Artery vs Saphenous Vein Graft After Prior Bypass Surgery: A Multicenter, Randomized Trial

Thursday, December 4, 2025

Submitted by

Vincent Sier

Source

Source Name: JACC Journals

Source URL: https://www.jacc.org/doi/10.1016/j.jacc.2025.09.1577

Author(s)

Ruben W. de Winter, Roel Hoek, Simon J. Walsh, Colm G. Hanratty, Ralf W. Sprengers, Jos W. R. Twisk, Iris Vegting, Stefan P. Schumacher, Michiel J. Bom, Niels J. Verouden, José P. Henriques, Adriaan Wilgenhof, Michele M. Viscusi, Koen Teeuwen, Maksymilian P. Opolski, Rafał Wolny, Pierfrancesco Agostoni, Jan-Peter van Kuijk, Bas E. Schölzel, Adriaan O. Kraaijeveld, Robert-Jan M. van Geuns, Maurits T. Dirksen, Antonius A.C.M. Heestermans, Jo Dens, Johan Bennett, Steven E. F. Haine, Ronak Delewi, Alexander Nap, James C. Spratt, Paul Knaapen

The PROCTOR trial randomized 220 post-coronary artery bypass grafting patients with saphenous vein graft (SVG) failure to native vessel percutaneous coronary intervention (PCI) (n=108) or SVG PCI (n=112). At one-year, major adverse cardiac events occurred in 34 percent with native PCI vs 19 percent with SVG PCI (HR 2.14; P=0.006). Nonfatal target-territory myocardial infarction (MI) was higher with native PCI (HR 2.12; P=0.029), as was repeat revascularization (HR 2.19; P=0.044). PCI-related MI occurred in 13 percent with native PCI and one percent with SVG PCI (HR 14.85; P=0.009). All-cause mortality did not differ (HR 1.59; P=0.472). SVG PCI produced significantly better one-year outcomes.