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Remote Ischemic Post-Conditioning of the Lower Limb During Primary Percutaneous Coronary Intervention Safely Reduces Enzymatic Infarct Size in Anterior Myocardial Infarction:
In this randomized trial involving 100 pts requiring PCI for STEMI and occluded LAD, half received lower extremity preconditioning for 3 cycles of 5min/5min ischemia/reperfusion. Preconditioning reduced enzymatic infarct size, reduced myocardial edema, and provided greater improvement in ST segment resolution.