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Slow Versus Fast Rewarming After Hypothermic Circulatory Arrest: Effects on Neuroinflammation and Cerebral Edema

Friday, November 6, 2020

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Source Name: European Journal of Cardio-Thoracic Surgery


Daniele Linardi, Beat Walpoth, Romel Mani, Angela Murari, Maddalena Tessari, Stiljan Hoxha, Marco Anderloni, Ilaria Decimo, Sissi Dolci, Elena Nicolato, Pietro Bontempi, Flavia Merigo, Giovanni B Luciani, Giuseppe Faggian, Alessio Rungatscher

This original article by Linardi et al. analysis the outcome of slow versus fast rewarming after hypothermic circulatory arrest in a rat model. They observed reduced inflammatory and oxidative stress and also a higher cerebral blood flow within the slow rewarming group compared to the fast rewarming group. Therefore they suspect slow rewarming might be superior regarding neurologic outcome after hypothermic circulatory arrest.

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