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Solitary Fibrous Tumors of the Pleura: Do We Need a Different Perspective on Malignancy?

Wednesday, March 27, 2024

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Source Name: European Journal of Cardio-Thoracic Surgery


Niels Michael Dörr, Marcus Krüger, Miriam Möller, Norman Zinne, Mario Toennies, Olaf Schega, Christoph Ritter, Steffen Decker, Antje Hölsken, Wolfgang Schütte, Christian Biancosino

This study aimed to evaluate the percentage of solitary fibrous pleural tumors presenting unfavorable clinical behavior to predict negative long-term outcomes. Although they are historically considered benign neoplasms, this retrospective review identified 25 percent of 74 patients displayed histological evidence of malignancy as per England criteria and the recurrence rate was 21 percent. The authors recommended the pathological differentiation of these tumors into pedunculated, well circumscribed, and sessile growth patterns. They also recommend that all nonpedunculated lesions should be classified as potentially aggressive.

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