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Statistical Primer: Sample Size and Power Calculations—Why, When, and How?

Tuesday, June 26, 2018

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Source Name: European Journal of Cardio-Thoracic Surgery


Graeme L Hickey, Stuart W Grant, Joel Dunning, Matthias Siepe

Sample size calculations are a necessary prerequisite in the design of clinical studies. Most often, they are encountered in randomized controlled trials. Hickey and colleagues describe the reasoning behind determinations of sample size and illustrate some basic calculations. The authors also discuss estimation and sample size for nonrandomized studies.


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