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Surgery Versus Surveillance: A Quality-of-Life Analysis of Patients With Moderately Dilated Aortic Root or Ascending Aorta

Thursday, November 20, 2025

Submitted by

EACTS Staff

Source

Source Name: European Journal of Cardio-Thoracic Surgery

Source URL: https://academic.oup.com/ejcts/article/67/9/ezaf288/8245820#google_vignette

Author(s)

Ming Hao Guo, Jehangir J Appoo, Philippe Demers, Hafsa ES, Arminder Jassar, Himanshu J Patel, William Brinkman, Maral Ouzounian, Rony Atoui, Juan B Grau, John Bozinovski, Michael W A Chu, Nimesh Desai, Francois Dagenais, G Chad Hughes, IV, Kevin Lachapelle, Zlatko Pozeg, Elaine E Tseng, Puja Kachroo, Richard Whitlock, Ismail El-Hamamsy, Cristian R Baeza, Anthony L Estrera, Eric Herget, George A Wells, Munir Boodhwani

This multicenter study from the TITAN trial examined the quality of life in 157 patients with moderate ascending thoracic aortic aneurysms (ATAA) undergoing surgery (n=52) or surveillance (n=105) between 2019 and 2022. After propensity matching and a 13-month follow-up using short form survey (SF)-36 questionnaires, surgical patients who underwent surgery showed significantly greater improvements compared to those receiving surveillance in mental component summary scores, general health, and mental health. The study concluded that surgical treatment of moderate ATAAs improves the mental aspects of quality of life at one year compared to surveillance.