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Transfusion of sex-mismatched and non–leukocyte-depleted red blood cells in cardiac surgery increases mortality
The authors analyzed long-term outcomes after cardiac surgery in nearly 10,000 patients to evaluate the mortality risk of blood transfusion. Sex-mismatched transfusion increased mortality, and use of non-leukocyte-depleted blood was associated with increased mortality. The age of the blood productes was not related to mortality.