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Journal and News Scan

Source: Heart
Author(s): Vincent Johan Nijenhuis, Jorn Brouwer, Lars Søndergaard, Jean-Philippe Collet, Erik Lerkevang Grove, Jurrien Maria Ten Berg

This review provides a comprehensive overview of the available data on antithrombotic therapy after transcatheter aortic valve replacement.

Antiplatelet therapy (APT) is favored over the use of a vitamin K antagonist (VKA) due to the lower risk of major bleeding associated with APT. Single APT is preferred over dual APT, but dual APT may be required for patients who had an acute coronary syndrome in the previous 6 months, who have complex coronary stenting, who have large aortic arch atheromas, or who had suffered a previous noncardioembolic stroke. VKA monotherapy may be needed for patients with atrial fibrillation or other indications for long-term oral anticoagulation.

Antithrombotic therapy should be selected according to the early device-related risks and the patient’s underlying thrombotic risk. APT should be selected as the primary treatment over VKA unless other indications for VKA are present.

Source: News from around the web.
Author(s): Claire Vernon

Patient Care and General Interest

In this brief video, an oncologist shares some thoughts on the value of tumor board discussions and the importance of having them early in a patient’s care.

 

Drugs and Devices

The US Food and Drug Administration has given Investigational Device Exemption approval to the RejuvenAir System from CSA Medical, a bronchoscopic system that uses liquid nitrogen for targeted treatment in chronic obstructive pulmonary disease with chronic bronchitis.

 

Research, Trials, and Funding

Research presented at the recent Annual Meeting of the International Society for Heart and Lung Transplantation reports on the success of an approach to organ recovery and evaluation for transplant that is based on military-style Special Ops teams.

An association between coffee intake and lung cancer risk, as reported by researchers at the recent Annual Meeting of the American Association for Cancer Research, is noted as interesting but not a finding that should distract from the contribution of smoking to lung cancer.

Biomedical engineering researchers from the University of Arkansas in the USA applied vector flow imaging to improve ultrasound assessment of the heart in two children, demonstrating the feasibility of the technology.

Source: The Hollywood Reporter
Author(s): Dave Brooks

Mick Jagger has undergone a TAVR procedure in New York and is now recovering.

Source: AORN Newsroom
Author(s): Association of Perioperative Registered Nurses (AORN)

Colorado becomes the second state (after Rhode Island) to require hospitals and ambulatory surgical centers to implement a surgical smoke evacuation system that prevents human exposure to surgical smoke. Effective May 1, 2021, all planned procedures in Colorado which are likely to generate surgical smoke must be conducted in facilities with policies and equipment in place to prevent human exposure to the smoke. According to the estimates of AORN, each year 500,000 healthcare workers, including surgeons, nurses, anesthesiologists, and other staff in the operating room, are exposed to laser or electrosurgical smoke, which can lead to serious and life-threatening respiratory diseases.

Source: The New England Journal of Medicine
Author(s): Alvin Rajkomar, Jeffrey Dean, Isaac Kohane

In this review, biomedical informatics experts explain what machine learning is with illustrative examples, and they discuss how machine learning can help the work of clinicians including diagnosis, treatment, prognosis, optimizing clinician workflow, and expanding the availability of clinical expertise. The major challenges and vulnerabilities of machine learning are also expounded.

Source: The Annals of Thoracic Surgery
Author(s): Dachuan Gu, Xue Zhang, Xiaolin Diao, Wei Zhao, Zhe Zheng

Gu and colleagues developed a surgeon-specific quality monitoring system using a structured database of information derived from electronic health records. Additionally, they used a mobile-based system to provide feedback to surgeons on risk-adjusted mortality, risk-adjusted complications, and other quality measures. The authors report on both the development of the system and the quality measures of top, middle, and bottom performing surgeons, with differences observed only for the rate of internal mammary artery use, the risk-adjusted postoperative length of stay, and risk-adjusted hospitalization cost. They conclude that the system allowed surgeons to compare their own surgical quality with that of their colleagues and identify priorities for improvement.

Source: The New England Journal of Medicine
Author(s): Sreekanth Vemulapalli, John D. Carroll, Michael J. Mack, Zhuokai Li, David Dai, Andrzej S. Kosinski, Dharam J. Kumbhani, Carlos E. Ruiz, Vinod H. Thourani, George Hanzel, Thomas G. Gleason, Howard C. Herrmann, Ralph G. Brindis, Joseph E. Bavaria

In light of the recent Centers for Medicare and Medicaid Services recommendation for transcatheter aortic valve replacement (TAVR) volumes, this study looked at 113,662 TAVRs from the TVT registry from 2015 to 2017 and found that 30-day mortality was higher at low-volume TAVR hospitals or low-volume operators.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Alex Fourdrain, Florence De Dominicis, Jules Iquille, Sophie Lafitte, Geoni Merlusca, Alejandro Witte-Pfister, Jonathan Meynier, Patrick Bagan, Pascal Berna

Intraoperative conversion may be necessary during video-assisted thoracoscopic surgery (VATS) for lung cancer. In this study on 610 patients, Fourdrain and colleagues observed that conversion during a VATS procedure was not associated with worse outcomes than undergoing an up-front thoracotomy. The authors conclude that thoracoscopic access should be preferred to thoracotomy, since conversion is not disadvantageous.

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): John S. Ikonomidis, Phillippe Menasche, Daniel Kreisel, Frank W. Sellke, Y. Joseph Woo, Yolonda L. Colson

Surgeon-scientists have been instrumental in many breakthroughs that have improved the lives of millions of patients. However, despite the many rewards that a career as a surgeon-scientist offers, the number of surgeons pursuing such a path has been steadily declining.

In this thoughtful editorial, Dr Ikonomidis and other cardiothoracic leaders explore the root causes for this decline and possible solutions for keeping a surgeon-scientist activity.

Source: Endo Research and Practice
Author(s): Arturo Evangelista, Giuliana Maldonado , Domenico Gruosso, Laura Gutiérrez, Chiara Granato, Nicolas Villalva, Laura Galian, Teresa González-Alujas, Gisela Teixido, Jose Rodríguez-Palomares

Although computed tomography is the most used imaging technique in the diagnosis of acute aortic syndrome, echocardiography offers complementary information for diagnosis and management in the emergency room, operting rooom, and catheter lab. In this review, Evangelista and associates explore the current role of echocardiography in the diagnosis and management of patients with acute aortic syndrome based on its advantages and limitations.

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