This article from the BBC highlights two different artificial intelligence (AI) diagnostic systems, one that evaluates coronary artery disease (CAD) and another that determines whether a lung nodule is cancerous. The systems are being trialed around the UK, and they show promise for improved accuracy of imaging-based diagnoses.
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Lung - Cancer
December 14, 2017
Using propensity score matching, patients with clinical stage I NSCLC who underwent either VATS lobectomy or stereotactic body radiotherapy (SBRT) were compared for long-term outcomes. Among 37 matched pairs, tumor control at 3 years was twice as good for surgery (p=.0038), cancer-specific survival was 15 percentage points better for surgery (p=.05
December 13, 2017
As many will recall, world chess champion Garry Kasparov was defeated by IBM's Deep Blue computer in 1997. Now machine-learning algorithms have bested trained pathologists in differentiating between benign and malignant changes in sentinel lymph nodes in breast cancer patients. We can expect to see increasing involvement of AI in pathology as well
December 13, 2017
Liquid biopsies have long held promise for diagnosis, treatment selection, and surveillance of lung cancer patients. This articles summarizes results of two studies involving highly precise measurement of tumor mutational burden. A burden of 16-fold or greater was associated with improved overall survival with immunotherapy (atezolizumab) compared
December 8, 2017
Patient Care
US states that implemented policies for screening newborns for critical congenital heart disease have seen reductions in infant cardiac deaths compared to states that didn’t implement screening.
November 27, 2017
Newspaper and prime time TV advertisements are beginning in the US today that detail the medical toll that smoking exacts on its victims. The ads are paid for by big tobacco based on a court order from 2006 that has finally survived the appeal process. A spokesperson for one of the companies stated that they hope to "develop less risky tobacco prod
November 17, 2017
Patient Care
November 8, 2017
This multicenter retrospective study sought to assess the utility of PET in the diagnosis of pulmonary nodules. It emphasized the inclusion of patient cohorts from different geographic regions and who underwent PET for different indications such as lung cancer screening or surgical evaluation. Among 1188 patients the positive predicted value was 86
October 31, 2017
In this single institution study, the authors screened biorepository materials obtained from patients undergoing resection for early stage cancer. They wished to identify serum markers related to early recurrence. A 7-component panel was developed that had a negative predictive value of 83% and an accuracy of 78%. The accuracy was 70%.
October 24, 2017
A useful reminder of the substantial progress that has been made and the continuing challenges that we face in fighting this terrible disease.