A small histopathological study of SARS and influenza autopsies compared to rejected for transplantation lungs. There is some speculation on the popular procoagulopathic nature of the panvirus, based on expression of angiotensin converting enzyme 2.There might be a collateral stimulus for lung preservation in organ retrieval.
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Lung - Other
April 13, 2020
Topical review on the epidemic in Britain, with a number of observations that relate to the cardiothoracic surgeons and all healthcare professionals: -The assertion that the National Health Service in Britain was overrun PRIOR to the pandemic. -The assertion that acute angina is now being undertreated.
March 18, 2020
The authors describe a thoughtful process for resource utilization in the setting of competing needs that optimizes survival for a popultion. Examples of existing guidelines are provided.
December 4, 2019
Well-presented Canadian prospective study juxtaposing a combination of Wells scoring and dimers to the imaging gold standard. It was particularly fascinating to read the referenced assertion that:
Evaluation of the INSPIRE Trial and Its Implications for Lung Transplantation With Normothermic Portable Ex Vivo Lung Perfusion
October 30, 2019
A balanced appraisal of last year's manuscript from the Lancet Group on a relatively novel portable Organ Care System for donor lungs. The analysis of the technical complications, especially organ damage from overenthusiastic revving of the pump, is particularly sobering.
October 9, 2019
Ex vivo lung perfusion was used in 25% of transplanted lungs in the Toronto program since 2008. This resulted in an increase in the number of transplanted patients without any degradation of long-term outcomes, including survival and freedom from chronic dysfunction.
Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report
September 5, 2019
The January update of an expert panel from the American College of Chest Physicians on the expanding clinical entity of pulmonary hypertension, especially pertinent to the transplant community.
August 21, 2019
An interesting discussion in this manuscript of a case-control study of 666 subjects.
August 20, 2019
Interesting follow-up study of 208 pulmonary ground -glass opacities in 160 subjects, with a yield of three adenocardinomas.
August 14, 2019
A comprehensive audio lecture from an academic pathologist on non-malignant pulmonary lesions.