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Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability

Wednesday, December 4, 2019

Submitted by

Aristotle Protopapas

Source

Source Name: The New England Journal of Medicine

Source URL: https://www.nejm.org/doi/full/10.1056/NEJMoa1909159?query=TOC

Author(s)

Clive Kearon, Kerstin de Wit, Sameer Parpia, Sam Schulman, Marc Afilalo, Andrew Hirsch, Frederick A. Spencer, Sangita Sharma, Frédérick D’Aragon, Jean-François Deshaies, Gregoire Le Gal, Alejandro Lazo-Langner, Cynthia Wu, Lisa Rudd-Scott, Shannon M. Bates, and Jim A. Julian, M.Math. for the PEGeD Study Investigators

Well-presented Canadian prospective study juxtaposing a combination of Wells scoring and dimers to the imaging gold standard.

It was particularly fascinating to read the referenced assertion that:

.....the prevalence of pulmonary embolism among patients who undergo diagnostic testing is substantially higher in Europe than in North America.. (Penultimate paragraph): We wonder what would be the robust causes of such disparity........

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