In an analysis from the SYNTAX trial that randomized PCI vs CABG in patients with complex coronary disease, Milojevic et al found that patients had significantly higher rates of cardiac death after PCI, which was particularly caused by significantly higher rates of myocardial infarction-related death.
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Coronary Disease - PCI
January 23, 2016
November 17, 2015
The authors report on the extended follow-up of Courage Trial patients for up to 15 years. In this trial, patients with chronic stable angina were randomized to medical therapy alone versus PCI plus medical therapy. At extended follow-up, there was no difference in overall survival between the two treatment strategies.
September 24, 2015
The investigators of this study compared survival of bare metal stent percutaneous coronary intervention (BMS-PCI) versus drug-eluting stent PCI (DES-PCI) versus single artery CABG (SA-CABG) versus multiarterial CABG (MA-CABG) in patients with multivessel coronary artery disease.
Outcomes of Percutaneous Coronary Intervention Performed at Offsite Versus Onsite Surgical Centers in the United Kingdom
July 20, 2015
The authors of this paper investigated the outcomes of percutaneous coronary intervention (PCI) performed in centers with and without cardiac surgical support onsite in a large database in the United Kingdom between 2006 and 2012. They found in multivarate analysis that there was no difference at 30 days, 1 year or 5 years.
March 29, 2015
The authors of this article compared CABG and PCI with second generation drug eluting stents (DES-PCI) in patients with multivessel coronary artery disease. They used data from a large observational registry and applied propensity score matching to create groups with similar baseline characteristics.
Survival probability loss from percutaneous coronary intervention compared with coronary artery bypass grafting across age groups
March 28, 2015
Benedetto and co-authors analyzed propensity-matched groups of patients who underwent CABG or PCI (n= 1097 pairs) for multivessel disease, and found that outcomes were comparable at 1-year follow-up, while CABG did significantly better during follow-up to 5 years and Kaplan-Meier curves continued to diverge even further after 5 years.
Optimal Medical Therapy Improves Clinical Outcomes in Patients Undergoing Revascularization with Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: Insights from the SYNTAX Trial at 5-Year Follow-Up
March 16, 2015
In this manuscript the authors present a post-hoc study of the SYNTAX trial. They compare outcomes between those patients on optimal medical therapy (OMT) and non-optimal medical therapy following revascularization for complex coronary artery disease (CAD).
Coronary Artery Surgery Versus Percutaneous Coronary Intervention in Octogenarians: Long-Term Results
February 2, 2015
Propensity-score matched patients undergoing PCI or CABG in regional centers in Emilia-Romagna, Italy, 2002-2008 were evaluated for long-term outcomes.
Long-term forecasting and comparison of mortality in the Evaluation of the Xience Everolimus Eluting Stent vs. Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization (EXCEL) trial: prospective validation of the SYNTAX Score II
January 20, 2015
The investigators of this project aimed to validate the SYNTAX Score II. This is a risk prediction tool that combines clinical characteristics and the original anatomical SYNTAX score in order to make 4 year mortality predictions with PCI or CABG in patients with unprotected left main disease (ULMCA) and an original SYNTAX score <33).
January 18, 2015
This is an interesting review of the current status of hybrid coronary revascularization (HCR). The authors discuss the merits and disadvantages of simultaneous versus staged procedures and describe the individual components of HCR. They also analyze the current evidence with regards to results and suggest indications for this type of therapy.